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Affordability Check

How to afford ACTIMMUNE

Generic name: Interferon gamma-1b

Pick how you're covered. We'll show you the cheapest legitimate way to get ACTIMMUNE — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.

How are you covered for prescriptions?

Pick the one that fits you. We'll show you the cheapest way to get this drug.

Pick an option above to see your specific path.

Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.

About ACTIMMUNE and its cost

What is this medication?

ACTIMMUNE is a prescription biologic medication, specifically a form of interferon gamma-1b, which is a protein that acts like one naturally produced by the human body. It is primarily used to reduce the frequency and severity of serious infections in patients with Chronic Granulomatous Disease, or CGD. This is a rare inherited condition where certain white blood cells are unable to effectively kill specific types of bacteria and fungi, making the individual more susceptible to life-threatening infections.

ACTIMMUNE is made by Horizon --- **Verification of current ownership:** Actimmune (interferon gamma-1b) is a biologic drug used to treat chronic granulomatous disease and malignant osteopetrosis. The rights to the drug were acquired by **Horizon Therapeutics** (formerly Horizon Pharma) in 2014. While **Amgen** acquired Horizon Therapeutics in October 2023, Horizon remains the primary manufacturer and legal holder of the Biologics License Application (BLA) in official FDA records (such as the Purple Book). Following the instruction to strip legal suffixes and descriptors like "Therapeutics" (which is analogous to "Pharmaceuticals"), the core company name is **Horizon**.. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.

Common questions

What's the cheapest way to afford ACTIMMUNE?

It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.

Can I use a copay card with Medicare for ACTIMMUNE?

No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Horizon --- **Verification of current ownership:** Actimmune (interferon gamma-1b) is a biologic drug used to treat chronic granulomatous disease and malignant osteopetrosis. The rights to the drug were acquired by **Horizon Therapeutics** (formerly Horizon Pharma) in 2014. While **Amgen** acquired Horizon Therapeutics in October 2023, Horizon remains the primary manufacturer and legal holder of the Biologics License Application (BLA) in official FDA records (such as the Purple Book). Following the instruction to strip legal suffixes and descriptors like "Therapeutics" (which is analogous to "Pharmaceuticals"), the core company name is **Horizon**. has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.

Does my Medicare Part D plan cover ACTIMMUNE?

Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.

How long does a Patient Assistance Program take?

Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.

What if I have a high-deductible plan?

For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.

Are there charity grants for Immunodeficiency Disorder?

Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.

More about ACTIMMUNE