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Affordability Check

How to afford Arcalyst

Generic name: rilonacept

Pick how you're covered. We'll show you the cheapest legitimate way to get Arcalyst — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.

How are you covered for prescriptions?

Pick the one that fits you. We'll show you the cheapest way to get this drug.

Pick an option above to see your specific path.

Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.

About Arcalyst and its cost

What is this medication? Arcalyst, known generically as rilonacept, is an injectable medication used to treat several rare inflammatory conditions. It is specifically approved for the treatment of Cryopyrin-Associated Periodic Syndromes, including Familial Cold Autoinflammatory Syndrome and Muckle-Wells Syndrome, in adults and children aged 12 and older. It is also used to maintain remission of Deficiency of IL-1 Receptor Antagonist and to treat recurrent pericarditis, an inflammatory condition affecting the sac around the heart, in patients 12 years of age and older.

This medication functions as an interleukin-1 blocker, meaning it binds to and neutralizes specific proteins in the body that cause inflammation. By blocking these signals, Arcalyst helps to reduce the overactive immune response responsible for symptoms such as joint pain, fever, and chest pain. It is usually administered by a healthcare provider or through self-injection under the skin on a weekly basis, helping to prevent the recurrence of flares and manage chronic inflammation associated with these disorders.

Arcalyst is made by Kiniksa. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.

Common questions

What's the cheapest way to afford Arcalyst?

It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.

Can I use a copay card with Medicare for Arcalyst?

No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Kiniksa has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.

Does my Medicare Part D plan cover Arcalyst?

Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.

How long does a Patient Assistance Program take?

Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.

What if I have a high-deductible plan?

For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.

Are there charity grants for Autoinflammatory Syndrome?

Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.

More about Arcalyst