Affordability Check
How to afford Evkeeza
Generic name: evinacumab
Pick how you're covered. We'll show you the cheapest legitimate way to get Evkeeza — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About Evkeeza and its cost
What is this medication? Evkeeza is a prescription injectable medication used in combination with other lipid-lowering treatments for adults and children aged 5 years and older who have homozygous familial hypercholesterolemia. This is a rare genetic disorder that results in dangerously high levels of low-density lipoprotein cholesterol, also known as bad cholesterol, which significantly increases the risk of early heart disease. The drug belongs to a class of medications called angiopoietin-like 3 inhibitors and is delivered via an intravenous infusion administered by a healthcare professional once every four weeks.
The primary function of this medication is to block a specific protein that regulates fat metabolism in the liver. By inhibiting this protein, the drug helps the body clear low-density lipoprotein cholesterol from the blood through pathways that do not rely on traditional receptors used by other cholesterol medications. It is specifically indicated for patients with the homozygous form of familial hypercholesterolemia and is not intended for people with other causes of high cholesterol or those whose condition is not caused by this specific genetic mutation.
Evkeeza is made by Regeneron. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford Evkeeza?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for Evkeeza?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Regeneron has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover Evkeeza?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Familial Hypercholesterolemia?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about Evkeeza
Full Evkeeza drug page
FDA label, prior authorization rules, full indications list
More options for Familial Hypercholesterolemia
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3