Affordability Check
How to afford GIVLAARI
Generic name: givosiran sodium
Pick how you're covered. We'll show you the cheapest legitimate way to get GIVLAARI — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About GIVLAARI and its cost
What is this medication? GIVLAARI is a prescription medication used for the treatment of adults with acute hepatic porphyria, which is a group of rare genetic disorders. These conditions are characterized by the buildup of toxic molecules in the body, leading to sudden and severe attacks of abdominal pain, neurological issues, and other serious complications. This medicine is specifically designed to reduce the frequency of these attacks and improve the quality of life for patients living with this chronic condition.
The medication works through a process called RNA interference to target a specific enzyme in the liver. By lowering the levels of this enzyme, the drug helps to prevent the accumulation of the toxic intermediates delta-aminolevulinic acid and porphobilinogen. It is typically administered as a subcutaneous injection by a healthcare provider on a monthly basis to provide consistent management of the disease.
GIVLAARI is made by Alnylam. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford GIVLAARI?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for GIVLAARI?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Alnylam has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover GIVLAARI?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Porphyria?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about GIVLAARI
Full GIVLAARI drug page
FDA label, prior authorization rules, full indications list
More options for Porphyria
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3