Skip to main content
RxCopaysGet started

Affordability Check

How to afford Kalydeco

Generic name: ivacaftor

Pick how you're covered. We'll show you the cheapest legitimate way to get Kalydeco — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.

How are you covered for prescriptions?

Pick the one that fits you. We'll show you the cheapest way to get this drug.

Pick an option above to see your specific path.

Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.

About Kalydeco and its cost

What is this medication? Kalydeco is a prescription medicine used for the treatment of cystic fibrosis in patients who have specific genetic mutations. Cystic fibrosis is a chronic condition that causes thick, sticky mucus to build up in the lungs, digestive tract, and other parts of the body. Unlike some other medications that only manage symptoms, this drug is designed to target the underlying cause of the disease by addressing the protein defect responsible for the condition.

The active ingredient in this medication is ivacaftor, which acts as a CFTR potentiator. It works by helping the defective proteins on the surface of cells stay open longer, which allows for a better flow of salt and water across cell membranes. This process helps to thin the mucus in the lungs and other organs, making it easier to clear and improving overall lung function. It is typically prescribed for adults and children who meet specific age and weight requirements and have been confirmed to have a responsive mutation through genetic testing.

Kalydeco is made by Vertex Pharmaceuticals. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.

Common questions

What's the cheapest way to afford Kalydeco?

It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.

Can I use a copay card with Medicare for Kalydeco?

No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Vertex Pharmaceuticals has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.

Does my Medicare Part D plan cover Kalydeco?

Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.

How long does a Patient Assistance Program take?

Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.

What if I have a high-deductible plan?

For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.

Are there charity grants for Cystic Fibrosis?

Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.

More about Kalydeco