Affordability Check
How to afford LONSURF
Generic name: trifluridine and tipiracil
Pick how you're covered. We'll show you the cheapest legitimate way to get LONSURF — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About LONSURF and its cost
What is this medication? Lonsurf is a combination prescription medicine containing two active ingredients, trifluridine and tipiracil. It is primarily used to treat adults with a type of colorectal cancer that has spread to other parts of the body, also known as metastatic colorectal cancer. This medication is typically prescribed for patients who have already received previous treatments, including specific types of chemotherapy and biological therapies, but whose cancer has continued to progress.
In addition to colorectal cancer, Lonsurf is also approved for treating adults with metastatic gastric cancer or gastroesophageal junction adenocarcinoma. This application is specifically for patients who have been previously treated with at least two prior lines of chemotherapy for their advanced disease. The trifluridine component works by incorporating into the DNA of cancer cells to stop them from growing, while tipiracil helps maintain high levels of trifluridine in the bloodstream by preventing its breakdown.
LONSURF is made by Taiho. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford LONSURF?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for LONSURF?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Taiho has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover LONSURF?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Gastric Cancer?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about LONSURF
Full LONSURF drug page
FDA label, prior authorization rules, full indications list
More options for Gastric Cancer
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3