Affordability Check
How to afford LUMAKRAS
Generic name: sotorasib
Pick how you're covered. We'll show you the cheapest legitimate way to get LUMAKRAS — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About LUMAKRAS and its cost
What is this medication? LUMAKRAS, which is also known by its generic name sotorasib, is a prescription medication used to treat adults with a specific type of lung cancer called non-small cell lung cancer. This treatment is specifically indicated for patients whose cancer has spread to other parts of the body or cannot be removed by surgery and possesses a unique genetic mutation known as KRAS G12C. It is typically prescribed for individuals who have already undergone at least one other form of systemic cancer therapy but have not seen sufficient improvement or have seen their cancer progress.
The medication works as a targeted therapy that inhibits the specific KRAS G12C protein, which normally sends signals that tell cancer cells to grow and divide. By binding to and inactivating this mutated protein, the drug helps to slow down or stop the growth of tumors. LUMAKRAS is usually taken as a daily oral tablet and represents a specialized approach to cancer treatment by focusing on the underlying molecular drivers of the disease rather than affecting all rapidly dividing cells in the body.
LUMAKRAS is made by Amgen. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford LUMAKRAS?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for LUMAKRAS?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Amgen has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover LUMAKRAS?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Colorectal Cancer?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about LUMAKRAS
Full LUMAKRAS drug page
FDA label, prior authorization rules, full indications list
More options for Colorectal Cancer
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3