Affordability Check
How to afford NAGLAZYME
Generic name: galsulfase
Pick how you're covered. We'll show you the cheapest legitimate way to get NAGLAZYME — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About NAGLAZYME and its cost
What is this medication? Naglazyme is a prescription medication used to treat a rare inherited disorder called Mucopolysaccharidosis VI, also known as Maroteaux-Lamy syndrome. This condition is caused by a deficiency in an enzyme required to break down certain complex carbohydrates in the body. When these substances are not processed correctly, they accumulate in the tissues and organs, which can lead to a variety of progressive physical symptoms and serious health issues over time.
The medicine functions as an enzyme replacement therapy by supplying the specific human enzyme that the patient's body is unable to produce on its own. By facilitating the breakdown of stored materials within the cells, the treatment helps to manage the symptoms of the disease and can improve a patient's physical endurance, specifically regarding their ability to walk and climb stairs. It is typically administered through a weekly intravenous infusion under the supervision of a healthcare professional.
NAGLAZYME is made by BioMarin. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford NAGLAZYME?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for NAGLAZYME?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But BioMarin has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover NAGLAZYME?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Mucopolysaccharidosis?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about NAGLAZYME
Full NAGLAZYME drug page
FDA label, prior authorization rules, full indications list
More options for Mucopolysaccharidosis
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3