Affordability Check
How to afford OGSIVEO
Generic name: nirogacestat
Pick how you're covered. We'll show you the cheapest legitimate way to get OGSIVEO — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About OGSIVEO and its cost
What is this medication? OGSIVEO, which contains the active ingredient nirogacestat, is a prescription medication used to treat adults with progressing desmoid tumors who require systemic treatment. Desmoid tumors are rare, noncancerous growths that develop in the connective tissue, such as the tissues that connect, support, and surround bones, ligaments, and muscles. Although these tumors do not spread to other parts of the body, they can be locally aggressive, growing into nearby structures and causing significant pain, physical limitations, or other serious health complications.
This drug belongs to a class of medications known as gamma-secretase inhibitors. It works by blocking the activity of the gamma-secretase enzyme, which plays a role in the signaling pathways that allow desmoid tumor cells to grow and survive. By inhibiting this enzyme, the medication helps to shrink existing tumors or slow down their progression. It is typically taken in tablet form twice daily, and the specific dosage and treatment schedule are managed by a healthcare professional based on the individual patient's needs and response to the therapy.
OGSIVEO is made by SpringWorks Therapeutics. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford OGSIVEO?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for OGSIVEO?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But SpringWorks Therapeutics has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover OGSIVEO?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Soft Tissue Tumor?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about OGSIVEO
Full OGSIVEO drug page
FDA label, prior authorization rules, full indications list
More options for Soft Tissue Tumor
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3