Affordability Check
How to afford ONGENTYS
Generic name: opicapone
Pick how you're covered. We'll show you the cheapest legitimate way to get ONGENTYS — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About ONGENTYS and its cost
What is this medication? ONGENTYS is a prescription medication that contains the active ingredient opicapone. It is used as an add-on treatment for people with Parkinson’s disease who are currently taking levodopa and carbidopa. The medication is specifically designed to help patients who experience off episodes, which are periods when their regular Parkinson’s medicine is not working well and symptoms such as tremors, stiffness, or slow movement return.
This medication works as a COMT inhibitor, meaning it blocks a certain enzyme in the body that breaks down levodopa before it can reach the brain. By inhibiting this enzyme, ONGENTYS helps maintain higher and more consistent levels of levodopa in the bloodstream. This allows the primary medication to be more effective for a longer duration, helping to reduce the overall amount of off time a person experiences during the day.
ONGENTYS is made by Neurocrine. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford ONGENTYS?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for ONGENTYS?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Neurocrine has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover ONGENTYS?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Parkinson's Disease?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about ONGENTYS
Full ONGENTYS drug page
FDA label, prior authorization rules, full indications list
More options for Parkinson's Disease
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3