Affordability Check
How to afford Vyleesi
Generic name: bremelanotide
Pick how you're covered. We'll show you the cheapest legitimate way to get Vyleesi — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About Vyleesi and its cost
What is this medication? Vyleesi is a prescription medication used to treat acquired, generalized hypoactive sexual desire disorder, often referred to as HSDD, in premenopausal women. This condition is defined by a low sexual desire that causes the individual significant distress or interpersonal difficulty and is not the result of a medical condition, mental health issue, or the side effects of another drug. It is specifically for women who previously had no problems with sexual desire, regardless of the type of sexual activity, the situation, or the partner.
The medication contains the active ingredient bremelanotide and is administered via a subcutaneous injection into the abdomen or thigh. It is designed to be used as needed at least forty-five minutes before sexual activity is expected to occur. Users are advised not to take more than one dose in a twenty-four hour period and no more than eight doses in a month. Vyleesi is not meant to enhance sexual performance and should not be used by postmenopausal women or men.
Vyleesi is made by Cosette. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford Vyleesi?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for Vyleesi?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Cosette has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover Vyleesi?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Low Sexual Desire?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about Vyleesi
Full Vyleesi drug page
FDA label, prior authorization rules, full indications list
More options for Low Sexual Desire
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3