Affordability Check
How to afford Xtandi
Generic name: enzalutamide
Pick how you're covered. We'll show you the cheapest legitimate way to get Xtandi — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About Xtandi and its cost
What is this medication? Xtandi is a prescription medicine used to treat men with various forms of prostate cancer. It is categorized as an androgen receptor inhibitor and is primarily used when the cancer has spread to other parts of the body or when it no longer responds to treatments designed to lower testosterone levels. By targeting the hormones that prostate cancer cells require to multiply, this medication helps to slow the progression of the disease and can help improve overall survival outcomes for patients.
This medication is indicated for the treatment of metastatic castration-resistant prostate cancer, non-metastatic castration-resistant prostate cancer, and metastatic castration-sensitive prostate cancer. It functions by blocking the action of androgens, which are male hormones like testosterone that can cause prostate cancer cells to grow. By preventing these hormones from binding to receptors within the cancer cells, the medication interrupts the signaling process that triggers tumor growth and development.
Xtandi is made by Astellas. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford Xtandi?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for Xtandi?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Astellas has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover Xtandi?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Prostate Cancer?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about Xtandi
Full Xtandi drug page
FDA label, prior authorization rules, full indications list
More options for Prostate Cancer
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3