Affordability Check
How to afford Zileuton
Generic name: Zileuton
Pick how you're covered. We'll show you the cheapest legitimate way to get Zileuton — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About Zileuton and its cost
What is this medication? Zileuton is an oral prescription medication primarily used for the long-term prevention and chronic treatment of asthma in adults and children at least 12 years old. It belongs to a class of drugs known as leukotriene synthesis inhibitors, which work by blocking the body's production of specific inflammatory substances. By controlling these inflammatory responses, the medication helps to reduce the frequency and severity of asthma symptoms, such as wheezing, shortness of breath, and coughing.
This medication functions by specifically inhibiting the enzyme 5-lipoxygenase, thereby preventing the formation of leukotrienes that cause airway swelling and muscle constriction in the lungs. It is important to note that Zileuton is a maintenance treatment and should not be used to treat a sudden asthma attack, as it does not work fast enough to provide immediate relief. Patients taking this drug often require periodic blood tests to monitor liver function, as the medication can occasionally affect liver enzyme levels during the course of treatment.
Zileuton is made by a pharmaceutical manufacturer. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford Zileuton?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for Zileuton?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But the manufacturer has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover Zileuton?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Asthma Attack?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about Zileuton
Full Zileuton drug page
FDA label, prior authorization rules, full indications list
More options for Asthma Attack
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3