Directory
Conditions
1,213 conditions. Each page links to drugs that treat it, grants available for patients, and — where it's a rare disease — our sister UniteRare page.
- Surgical Dressing ChangeOther
- Surgical Wound CareOther
- SwellingOther
- Swimmer's EarInfectious Disease
- SyphilisInfectious Disease
- Systemic CandidiasisInfectious DiseaseRare
- Systemic Juvenile Idiopathic ArthritisMusculoskeletal
- Systemic Lupus ErythematosusAutoimmuneRare
- Systemic MastocytosisBlood DisordersRare
- Systemic Yeast InfectionInfectious Disease
- Systolic Heart FailureCardiovascular
- TachycardiaCardiovascular
- Taste DisorderNeurological
- Tension HeadacheNeurological
- Termination of PregnancyReproductive Health
- Testicular CancerCancer
- Testicular HypofunctionReproductive Health
- Therapeutic AnticoagulationBlood Disorders
- Therapeutic drug monitoringOther
- Thiamine DeficiencyMetabolic
- Thickened SkinDermatology
- Third-degree burnDermatology
- Third-degree burnsDermatology
- ThrombocytopeniaBlood Disorders
- ThrombophiliaBlood Disorders
- Thrombotic thrombocytopenic purpuraBlood DisordersRare
- Thyroid CancerCancer
- Thyroid DisorderEndocrine
- Thyroid Eye DiseaseOphthalmology
- Tinea versicolorDermatology
- Tooth DecayGastrointestinal
- Tourette SyndromeNeurological
- ToxoplasmosisInfectious Disease
- Transient Ischemic AttackNeurological
- Transwell):** 评估药物通过信号通路对细胞生长和运动能力的影响。 --- ### 3. 应用实例：以肿瘤药物研发为例 假设研发一种针对EGFR突变的肺癌靶向药： 1. **筛选：** 检测候选药物是否能抑制细胞内EGFR的自磷酸化。 2. **验证：** 使用Western Blot检测下游通路蛋白（如ERK、Akt）的磷酸化水平是否随药物浓度增加而下降。 3. **转录水平：** 通过qPCR检测下游调控细胞周期的基因（如Cyclin D1）表达是否被抑制。 4. **耐药：** 若细胞产生耐药，检测是否由于Met通路的代偿性激活引起。 ### 总结 信号通路检测不仅是评价药物效果的“标尺”，更是解析生命过程、指导临床精准用药的重要工具。通过多维度、多技术的联合应用，可以构建出药物作用的完整图谱。Other
- TrichomoniasisInfectious Disease
- Tubal InfertilityReproductive Health
- TuberculosisInfectious DiseaseRare
- Tuberculosis ScreeningInfectious Disease
- Tuberous SclerosisGenetic DisorderRare
- Tumor Lysis SyndromeMetabolic
- Type 1 DiabetesMetabolic
- Type 2 DiabetesMetabolic
- Type 2 Diabetes MellitusMetabolic
- Type 2 Diabetes with Autonomic NeuropathyMetabolic
- Type 2 Diabetes with Kidney DiseaseMetabolic
- TyrosinemiaMetabolic
- Ulcerative ColitisGastrointestinal
- Ulcerative Colitis and Crohn’s DiseaseGastrointestinal
- Ulcerative ProctitisGastrointestinal
- Uncomplicated DeliveryReproductive Health
- UnderweightMetabolic
- Undescended TestisReproductive Health
- Undiagnosed IllnessOther
- UnhappinessOther
- Unknown IllnessOther
- Unspecified IllnessOther
- Unspecified InjuryOther
- Unstable AnginaCardiovascular
- Upper Respiratory InfectionInfectious Disease
- Urea Cycle DisorderMetabolic
- Urge IncontinenceKidney & Urological
- Urinary IncontinenceKidney & Urological
- Urinary Tract DisorderKidney & Urological
- Urinary Tract InfectionInfectious Disease
- Urinary Tract Pain and IrritationKidney & Urological
- Uterine FibroidsReproductive Health
- Uterine InertiaReproductive Health
- UveitisOphthalmologyRare
- Vaginal Ring Birth ControlReproductive Health
- Vaginal Yeast InfectionInfectious Disease
- VaginitisReproductive Health
- Valley FeverInfectious DiseaseRare
- Varicose VeinsCardiovascular
- Vascular Graft InfectionInfectious Disease
- Vasodilatory ShockCardiovascular
- Vasomotor RhinitisRespiratory
- Ventilator DependenceRespiratory
- Ventricular FibrillationCardiovascular
- Ventricular TachycardiaCardiovascular
- Vernal ConjunctivitisOphthalmology
- Vernal KeratoconjunctivitisOphthalmologyRare
- VertigoNeurological
- Vesicoureteral RefluxKidney & Urological
- Viral Hepatitis ExposureInfectious Disease
- Viral WartsDermatology
- Visceral LeishmaniasisInfectious Disease
- Vision Correction FittingOphthalmology
- Vitamin A DeficiencyMetabolic
- Vitamin B DeficiencyMetabolic
- Vitamin B1 DeficiencyMetabolic
- Vitamin B12 Deficiency AnemiaBlood Disorders
- Vitamin B6 DeficiencyMetabolic
- Vitamin D DeficiencyMetabolic
- Vitamin DeficiencyMetabolic
- Vitamin K DeficiencyMetabolic
- Vitreous Syndrome Following Catarat SurgeryOphthalmology
- Vivax MalariaInfectious Disease
- Vulvar ItchingReproductive Health
- VulvodyniaReproductive Health