How much does Benzamycin cost?

Pricing for Benzamycin varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Benzamycin need prior authorization?

Benzamycin appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Benzamycin?

We haven't verified an active copay card or PAP for Benzamycin in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Benzamycin used to treat?

Benzamycin (generic: erythromycin and benzoyl peroxide) is indicated for Acne Vulgaris. Click any condition name on this page for more detail.

Does Benzamycin have a generic version?

The generic name for Benzamycin is erythromycin and benzoyl peroxide. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Benzamycin

Generic: erythromycin and benzoyl peroxide

Verified·Apr 23, 2026

Manufacturer: Bausch Health
NDC: 0187-5205
RxCUI: 213082
ICD-10 indication: L70.0

Affordability Check

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About Benzamycin

What is this medication? Benzamycin is a prescription topical gel used primarily for the treatment of inflammatory acne vulgaris. It is a combination medication that contains two active ingredients: erythromycin and benzoyl peroxide. Erythromycin belongs to a class of drugs known as macrolide antibiotics, while benzoyl peroxide is an antibacterial agent that also helps dry out the skin. Together, these components work more effectively than either ingredient used alone to reduce the overall number of acne lesions.

The medication works through a dual mechanism to target the primary causes of skin breakouts. Erythromycin helps to stop the growth of bacteria that contribute to inflammation, while benzoyl peroxide works to kill bacteria and reduce excess oil production. Additionally, benzoyl peroxide helps to unclog pores by promoting the shedding of dead skin cells. This combined approach helps to clear current pimples and prevent new ones from forming, though it often takes several weeks of consistent application to observe significant improvement.

Copay & patient assistance

Patient Copay Amount: Not Publicly Available
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: Medicaid patients whose insurance plans no longer provide coverage for Bausch Health products; must be prescribed single-source Bausch Health pharmaceuticals.
RxBIN, PCN, and Group numbers: Not Publicly Available

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for erythromycin and benzoyl peroxide.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Benzamycin →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for erythromycin and benzoyl peroxide →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Benzamycin. Official source: DailyMed (NLM) · Label effective Nov 30, 2020

Indications and usage

INDICATIONS AND USAGE Benzamycin Topical Gel is indicated for the topical treatment of acne vulgaris.

Dosage and administration

DOSAGE AND ADMINISTRATION Benzamycin Topical Gel should be applied twice daily, morning and evening, or as directed by a physician, to affected areas after the skin is thoroughly washed, rinsed with warm water and gently patted dry.

Contraindications

CONTRAINDICATIONS Benzamycin Topical Gel is contraindicated in those individuals who have shown hypersensitivity to any of its components.

Warnings

WARNINGS Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is one primary cause of “antibiotic-associated colitis”. After the diagnosis of pseudomembranous colitis has been established, therapeutic measures should be initiated. Mild cases of pseudomembranous colitis usually respond to drug discontinuation alone. In moderate to severe cases, consideration should be given to management with fluids and electrolytes, protein supplementation and treatment with an antibacterial drug clinically effective against C. difficile colitis.

Adverse reactions

ADVERSE REACTIONS In controlled clinical trials, the incidence of adverse reactions associated with the use of Benzamycin Topical Gel was approximately 3%. These were dryness and urticarial reaction. The following additional local adverse reactions have been reported occasionally: irritation of the skin including peeling, itching, burning sensation, erythema, inflammation of the face, eyes and nose, and irritation of the eyes. Skin discoloration, oiliness and tenderness of the skin have also been reported. To report SUSPECTED ADVERSE REACTIONS, contact Bausch Health US, LLC at 1-800-321-4576 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Use in pregnancy

Pregnancy: Teratogenic Effects: Animal reproduction studies have not been conducted with Benzamycin Topical Gel or benzoyl peroxide. There was no evidence of teratogenicity or any other adverse effect on reproduction in female rats fed erythromycin base (up to 0.25% diet) prior to and during mating, during gestation and through weaning of two successive litters. There are no well-controlled trials in pregnant women with Benzamycin Topical Gel. It also is not known whether Benzamycin Topical Gel can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Benzamycin Topical Gel should be given to a pregnant woman only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Acne Vulgaris

Medicare Part D coverage

How Benzamycin appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

2 of 5,509 plans

Most common tier

Tier 1

On 100% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	1	100%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 1 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.