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BREZTRI

Generic: budesonide, glycopyrrolate, and formoterol fumarate

Data may be stale·Apr 23, 2026
NDC
0310-4616
RxCUI
2387326
Route
RESPIRATORY (INHALATION)
ICD-10 indication
J44.9

Affordability Check

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About BREZTRI

What is this medication?

BREZTRI AEROSPHERE is a prescription inhalation medicine used for the long-term maintenance treatment of chronic obstructive pulmonary disease, also known as COPD. This condition includes chronic bronchitis and emphysema. The medication contains three active ingredients: budesonide, glycopyrrolate, and formoterol fumarate. These components work together to reduce inflammation in the lungs and help keep the airways open, which improves breathing and lung function for adults living with this chronic condition.

This medication is specifically designed to help prevent or reduce the frequency of COPD flare-ups or exacerbations. It is intended for regular use and should be taken twice daily as directed by a healthcare provider. It is important to note that BREZTRI is not a rescue medicine and should not be used to treat sudden breathing problems or acute attacks. Patients should always have a separate rescue inhaler available for the treatment of sudden symptoms.

Copay & patient assistance

  • Patient Copay Amount: As low as $0 for each 30-day supply (1 inhaler)
  • Maximum Annual Benefit Limit: Not Publicly Available (Subject to a maximum savings limit)
  • Core Eligibility Restrictions: Must have commercial (private) insurance. Patients enrolled in state or federally funded prescription insurance programs (including Medicare Part D, Medicaid, Medigap, VA, DOD, or TriCare) are not eligible. Must be a resident of the United States or a U.S. Territory.
  • RxBIN, PCN, and Group numbers: Not Publicly Available (Claims are processed via Pharmacy Data Management Inc as a secondary payer using Other Coverage Code 8)

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How BREZTRI appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).

Covered by plans

75%

4,120 of 5,499 plans

Most common tier

Tier 3

On 77% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)58
19%
Tier 2 (generic)9
3%
Tier 3 (preferred brand)236
77%
Tier 4 (non-preferred brand)2
1%

Step therapy: 0% of formularies

Quantity limits: 98% of formularies

Coverage breadth: 305 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.