BRUKINSA
Generic: zanubrutinib
- Manufacturer
- BeiGene
- NDC
- 72579-011
- RxCUI
- 2262440
- Route
- ORAL
- ICD-10 indication
- C88.0
Affordability Check
How much will you actually pay for BRUKINSA?
In 30 seconds, see every legitimate way to afford BRUKINSA — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About BRUKINSA
What is this medication?
Brukinsa, which contains the active ingredient zanubrutinib, is a prescription medicine used to treat several types of blood cancers in adults. It is primarily indicated for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. Additionally, it is used for individuals with Waldenstrom's macroglobulinemia, as well as certain cases of mantle cell lymphoma and marginal zone lymphoma where at least one prior therapy has already been attempted.
This medication functions as a kinase inhibitor by targeting a protein known as Bruton's tyrosine kinase. This protein is essential for the growth and survival of the malignant B-cells associated with these cancers. By blocking this protein, the drug helps to stop the spread of cancer cells and can lead to a reduction in tumor size. It is usually administered in the form of capsules that are swallowed whole, following a dosing schedule determined by a healthcare provider.
Copay & patient assistance
- Patient Copay Amount: Not Publicly Available
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Not Publicly Available
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for zanubrutinib.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup BRUKINSA →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for zanubrutinib →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How BRUKINSA appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
76%
4,180 of 5,499 plans
Most common tier
Tier 5
On 79% of covering formularies
Prior authorization required
99%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 59 | 18% |
| Tier 2 (generic) | 2 | 1% |
| Tier 4 (non-preferred brand) | 7 | 2% |
| Tier 5 (specialty) | 259 | 79% |
| Tier 6 | 1 | 0% |
Step therapy: 0% of formularies
Quantity limits: 86% of formularies
Coverage breadth: 328 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.
Rare-disease navigation (specialists, trials, patient communities)
BRUKINSA treats 5 rare conditions. For in-depth disease pages on our sister site:
- UniteRare · Lymphoma
- UniteRare · Follicular Lymphoma
- UniteRare · Mantle Cell Lymphoma
- UniteRare · Chronic Lymphocytic Leukemia
- UniteRare · Waldenström Macroglobulinemia
UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.