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BUFFERED PENICILLIN G POTASSIUM

Generic: BUFFERED PENICILLIN G POTASSIUM

Verified·Sep 7, 2026
Manufacturer
Pfizer
NDC
51662-1436
RxCUI
863538
Route
INTRAMUSCULAR
ICD-10 indication
A41.9

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About BUFFERED PENICILLIN G POTASSIUM

What is this medication? Buffered penicillin G potassium is a potent antibiotic medication used to treat a wide range of serious bacterial infections. As a member of the penicillin class, it works by inhibiting the synthesis of bacterial cell walls, which effectively kills the bacteria or stops them from spreading. Doctors typically prescribe this medication for severe conditions such as bacterial meningitis, endocarditis, and pneumonia. It is also an important treatment for specific diseases like syphilis, gas gangrene, and various types of blood poisoning caused by susceptible microorganisms.

In addition to treating active infections, this medication is sometimes used as a preventative measure for people with heart valve issues who are undergoing certain medical or dental procedures. It can also be utilized for managing infections in the bones, joints, and skin when these are caused by penicillin-sensitive bacteria. It is important to note that this drug only works against bacterial infections and has no effect on viruses, such as those that cause the common cold or flu. It is usually administered by injection or through an intravenous line in a clinical setting.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How BUFFERED PENICILLIN G POTASSIUM appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-07-31).

Covered by plans

71%

3,919 of 5,490 plans

Most common tier

Tier 4

On 54% of covering formularies

Prior authorization required

11%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)62
21%
Tier 2 (generic)64
22%
Tier 3 (preferred brand)8
3%
Tier 4 (non-preferred brand)158
54%
Tier 61
0%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 293 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.