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Chlorhexidine Gluconate

Generic: chlorhexidine gluconate

Unverified·never
Manufacturer
Xttrium
RxCUI
1245230
Route
TOPICAL
ICD-10 indication
K05.10

Affordability Check

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About Chlorhexidine Gluconate

What is this medication? Chlorhexidine gluconate is a prescription-strength antimicrobial mouthwash used primarily to treat gingivitis, which is characterized by the redness, swelling, and bleeding of the gums. This medication works by killing and preventing the growth of bacteria in the mouth that cause gum disease. It is often recommended for patients who need help managing oral inflammation or for those recovering from certain dental procedures where infection control is a priority.

The medication is typically used twice daily after brushing and flossing, requiring the patient to swish the solution for thirty seconds before spitting it out. It is important not to swallow the liquid or consume food and drink immediately after use to ensure the medication remains effective on the gum tissues. While it is highly effective at reducing bacteria and gum inflammation, it should only be used as directed by a healthcare professional, as it may cause temporary tooth staining or changes in taste during the treatment period.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Chlorhexidine Gluconate. Official source: DailyMed (NLM) · Label effective Dec 26, 2022

Indications and usage
Use healthcare personnel handwash: helps reduce bacteria that potentially can cause disease
Dosage and administration
Directions use with care in premature infants and infants under 2 months of age. These products may cause irritation or chemical burns. Healthcare personnel handwash: wet hands with water dispense about 5 mL of product into cupped hands and wash in a vigorous manner for 30 seconds rinse and dry thoroughly Healthcare personnel handwash: wet hands with water dispense about 5 mL of product into cupped hands and wash in a vigorous manner for 30 seconds rinse and dry thoroughly
Warnings
Warnings For external use only Allergy alert: This product may cause a severe allergic reaction. Symptoms may include: wheezing/difficulty breathing shock facial swelling hives rash If an allergic reaction occurs, stop use and seek medical help right away. Do not use if you are allergic to chlorhexidine gluconate or any other ingredient in this product When using this product keep out of eyes, ears, and mouth. May cause serious and permanent eye injury if permitted to enter and remain in the eye or may cause deafness when instilled in the middle ear through perforated eardrums. if solution should contact these areas, rinse out promptly and thoroughly with water do not use routinely if you have wounds which involve more than the superficial layers of the skin Stop use and ask a doctor if irritation, sensitization, or allergic reaction occurs. These may be signs of a serious condition. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Chlorhexidine Gluconate appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

69%

3,817 of 5,509 plans

Most common tier

Tier 1

On 82% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)269
82%
Tier 2 (generic)60
18%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 329 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.