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Cupric Chloride

Generic: CUPRIC CHLORIDE

Verified·Apr 23, 2026
Manufacturer
American Regent
NDC
72819-234
RxCUI
204536
Route
INTRAVENOUS
ICD-10 indication
E61.0

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About Cupric Chloride

What is this medication? Cupric chloride is a prescription mineral additive used in intravenous solutions for patients receiving total parenteral nutrition. It serves as a source of supplemental copper to help maintain normal blood levels and prevent deficiency in individuals who are unable to consume or absorb nutrients through a regular diet. Copper is an essential trace element required for several vital physiological processes, including the production of red blood cells and the maintenance of healthy bones, nerves, and immune function.

By providing this mineral directly into the bloodstream, the medication supports important enzymatic reactions that facilitate energy production and iron metabolism. It is administered by healthcare professionals in clinical settings as part of a larger nutritional regimen designed to meet a patient's daily metabolic requirements. Careful monitoring is typically performed by medical staff to ensure that copper levels remain within a safe and therapeutic range during the course of treatment.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Cupric Chloride. Official source: DailyMed (NLM) · Label effective Oct 16, 2024

Indications and usage
INDICATIONS AND USAGE Cupric chloride injection, USP is indicated for use as a supplement to intravenous solutions given for TPN. Administration helps to maintain copper serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
Dosage and administration
DOSAGE AND ADMINISTRATION Cupric Chloride Injection contains 0.4 mg copper/mL and is administered intravenously only after dilution. The additive should be diluted in a volume of fluid not less than 100 mL. For the adult receiving TPN, the suggested additive dosage is 0.5 to 1.5 mg copper/day (1.25 to 3.75 mL/day). For pediatric patients, the suggested additive dosage is 20 mcg copper/kg/day (0.05 mL/kg/day). Infants weighing less than 1500 gm may have increased requirements because of their low body reserves and increased requirements for growth. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. (See PRECAUTIONS .)
Contraindications
CONTRAINDICATIONS None known.
Warnings
WARNINGS Direct intramuscular or intravenous injection of cupric chloride injection is contraindicated, as the acidic pH of the solution (2) may cause considerable tissue irritation. Liver and/or biliary tract dysfunction may require omission or reduction of copper and manganese doses because these elements are primarily eliminated in the bile. WARNING: This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum. Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration.
Adverse reactions
ADVERSE REACTIONS None known.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.