How much does HYDROCORTISONE ACETATE cost?

Pricing for HYDROCORTISONE ACETATE varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does HYDROCORTISONE ACETATE need prior authorization?

HYDROCORTISONE ACETATE appears on 2 payer formularies in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for HYDROCORTISONE ACETATE?

We haven't verified an active copay card or PAP for HYDROCORTISONE ACETATE in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is HYDROCORTISONE ACETATE used to treat?

HYDROCORTISONE ACETATE (generic: Hydrocortisone Acetate) is indicated for Hemorrhoids, Corticosteroid-responsive dermatoses. Click any condition name on this page for more detail.

HYDROCORTISONE ACETATE

Generic: Hydrocortisone Acetate

Verified·Apr 23, 2026

NDC: 71335-2939
RxCUI: 1291082
Route: RECTAL
ICD-10 indication: K64.9

Affordability Check

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About HYDROCORTISONE ACETATE

What is this medication? Hydrocortisone acetate is a corticosteroid medication primarily used to reduce inflammation, itching, and swelling in various parts of the body. It works by mimicking the effects of hormones naturally produced by the adrenal glands, which helps to calm the immune response responsible for irritation. This medication is commonly prescribed for a wide range of skin conditions such as eczema, psoriasis, dermatitis, and various allergic reactions. It is available in several delivery methods, including topical creams, ointments, and lotions, as well as rectal suppositories or foams for treating localized internal inflammation. Beyond dermatological issues, hydrocortisone acetate is frequently utilized to provide relief from the discomfort associated with hemorrhoids and other inflammatory conditions of the rectal area. By shrinking swollen tissues and alleviating localized pain or burning, it helps patients manage symptoms during the recovery process. It is important to follow a healthcare provider's instructions regarding the frequency and duration of use, as prolonged application can lead to side effects like skin thinning or changes in pigmentation. This medication is intended for symptomatic relief and does not directly treat the root cause of viral or bacterial infections.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Hydrocortisone Acetate.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup HYDROCORTISONE ACETATE →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Hydrocortisone Acetate →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for HYDROCORTISONE ACETATE. Official source: DailyMed (NLM) · Label effective Oct 24, 2025

Indications and usage

INDICATIONS AND USAGE Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Dosage and administration

DOSAGE AND ADMINISTRATION Topical corticosteroids are generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.

Contraindications

CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Adverse reactions

ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Itching Irritation Dryness Folliculitis Hypertrichosis Acneiform eruptions Hypopigmentation Perioral dermatitis Allergic contact dermatitis Maceration of the skin Secondary infection Skin atrophy Striae Miliaria

Use in pregnancy

Pregnancy Teratogenic Effects: Pregnancy Category C – Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How HYDROCORTISONE ACETATE appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

259 of 5,509 plans

Most common tier

Tier 2

On 38% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	1	8%
Tier 2 (generic)	5	38%
Tier 3 (preferred brand)	4	31%
Tier 4 (non-preferred brand)	3	23%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 13 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.