How much does Hyoscyamine Sulfate cost?

Pricing for Hyoscyamine Sulfate varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Hyoscyamine Sulfate need prior authorization?

Hyoscyamine Sulfate appears on 4 payer formularies in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Hyoscyamine Sulfate?

We haven't verified an active copay card or PAP for Hyoscyamine Sulfate in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Hyoscyamine Sulfate used to treat?

Hyoscyamine Sulfate (generic: Hyoscyamine Sulfate) is indicated for Cystitis, Irritable Bowel Syndrome, Renal Colic and 1 other condition. Click any condition name on this page for more detail.

Hyoscyamine Sulfate

Generic: Hyoscyamine Sulfate

Verified·Apr 23, 2026

Manufacturer: Lannett
NDC: 51655-845
RxCUI: 1047905
Route: ORAL
ICD-10 indication: K58.9

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About Hyoscyamine Sulfate

What is this medication? Hyoscyamine sulfate is a prescription medication classified as an anticholinergic and antispasmodic drug. It works by blocking the action of acetylcholine, a natural chemical in the body, which helps to relax smooth muscles and reduce the production of various bodily secretions. This medication is primarily used to treat a range of gastrointestinal disorders, including irritable bowel syndrome, peptic ulcers, and colitis, by slowing the natural movements of the digestive tract and relieving cramps or spasms in the stomach and intestines.

Beyond digestive health, hyoscyamine sulfate is also utilized to manage symptoms related to bladder spasms, urinary tract inflammation, and certain types of heart conditions. It can help reduce excessive secretions in the respiratory tract and is sometimes used as a supportive treatment for Parkinson's disease to control tremors and rigidity. By relaxing the muscles in several organ systems and decreasing the output of stomach acid and saliva, the medication provides relief from pain and discomfort caused by overactive muscle activity.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

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GoodRx

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NeedyMeds

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RxAssist

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Prescribing information

From the FDA-approved label for Hyoscyamine Sulfate. Official source: DailyMed (NLM) · Label effective Jan 1, 2026

Indications and usage

INDICATIONS AND USAGE This product may be used in functional intestinal disorders to reduce symptoms such as those seen in mild dysenteries and diverticulitis. It can also be used to control gastric secretion, visceral spasm and hypermotility in cystitis, pylorospasm and associated abdominal cramps. Along with appropriate analgesics, this product is indicated in symptomatic relief of biliary and renal colic and as a drying agent in the relief of symptoms of acute rhinitis. This product is effective as adjunctive therapy in the treatment of peptic ulcer and irritable bowel syndrome, acute enterocolitis and other functional gastrointestinal disorders.

Dosage and administration

DOSAGE AND ADMINISTRATION Dosage may be adjusted according to the condition and severity of symptoms. May be taken with or without water. Adults and adolescents 12 years of age and older: 1 to 2 tablets orally three or four times a day, thirty minutes to one hour before meals and at bedtime. Dosage may be increased to every four hours as needed. Do not exceed 12 tablets in 24 hours. Note: Geriatric patients may be more sensitive to the effects of the usual adult dose.

Contraindications

CONTRAINDICATIONS Glaucoma, obstructive uropathy, obstructive diseases of the gastrointestinal tract, paralytic ileum, intestinal atony of elderly or debilitated patients, unstable cardiovascular status, severe ulcerative colitis, toxic megacolon, myasthenia gravis, and myocardial ischemia. This product is not recommended for use in children under twelve years of age.

Warnings

WARNINGS Heat prostration can occur with drug use in the event of high environmental temperature. Diarrhea may be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy or colostomy; in this instance, treatment would be inappropriate and possibly harmful. This product may cause drowsiness or blurred vision. Patients taking this product should be warned not to engage in activities requiring mental alertness such as operating a motor vehicle or other machinery or to perform hazardous tasks while taking this drug.

Drug interactions

Drug Interactions: Absorption of other oral medications may be decreased during concurrent use with anticholinergics due to decreased gastrointestinal motility and delayed gastric emptying. Drug interactions may occur when anticholinergics are used with the following medications: antacids, antidiarrheals (adsorbent), other anticholinergics, antimyasthenics, cyclopropane, haloperidol, ketoconazole, metoclopramide, opioid (narcotic) analgesics, and potassium chloride.

Adverse reactions

ADVERSE REACTIONS Not all of the following adverse reactions have been reported with hyoscyamine sulfate. The following adverse reactions have been reported for pharmacologically similar drugs with anticholinergic/ antispasmodic action. Adverse reactions may include dryness of the mouth, urinary hesitancy and retention; blurred vision; tachycardia; palpitations; mydriasis; cycloplegia; increased ocular tension; loss of taste; headache; nervousness; drowsiness; weakness; dizziness; insomnia; nausea; vomiting; impotence; suppression of lactation; constipation; bloated feeling; allergic reactions or drug idiosyncrasies; urticaria and other dermal manifestations; ataxia; speech disturbance; some degree of mental confusion and/or excitement (especially in elderly persons); and decreased sweating.

Use in pregnancy

Pregnancy: Pregnancy Category C. Animal reproduction studies have not been conducted with this product. It is also not known whether this product can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Hyoscyamine crosses the placenta. This product should be given to a pregnant woman only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.