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Ionite APF Foam

Generic: Sodium Fluoride

Verified·Apr 23, 2026
Manufacturer
Dharma Research, Inc.
NDC
53045-250
RxCUI
831719
Route
DENTAL
ICD-10 indication
Z29.3

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About Ionite APF Foam

What is this medication? Ionite APF Foam is a prescription-strength topical fluoride treatment used by dental professionals to help prevent tooth decay and strengthen tooth enamel. It contains 1.23 percent fluoride ion and is formulated with an acidic pH to facilitate faster and deeper fluoride uptake into the tooth structure. This professional-grade foam is typically applied during a routine dental visit using a tray system, where it remains in contact with the teeth for one to four minutes to provide protection against cavities. This medication works by promoting the remineralization of weakened enamel and making the teeth more resistant to acid attacks from bacteria and dietary sugars. It is especially beneficial for children and adults who are at a high risk for dental caries or those who have specific conditions that make them more prone to enamel erosion. After the foam application, patients are usually advised to refrain from eating, drinking, or rinsing their mouths for at least thirty minutes to allow the fluoride to fully integrate into the tooth surfaces.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Ionite APF Foam. Official source: DailyMed (NLM) · Label effective Oct 27, 2020

Warnings and precautions
Do not swallow. Keep out of reach of children. Contents under pressure. Do not place in hot water or near radiators, stoves or other sources of heat. Do not puncture or incinerate container. Do not spray towards open flames. For professional use only.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.