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Iris 60 Second APF

Generic: Sodium Fluoride

Verified·Apr 23, 2026
NDC
66975-050
RxCUI
245593
Route
DENTAL
ICD-10 indication
Z29.3

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About Iris 60 Second APF

What is this medication? Iris 60 Second APF is a prescription-strength topical fluoride treatment formulated as an acidulated phosphate fluoride gel or foam. This medication is typically administered by dental professionals during routine office visits to help prevent dental caries, also known as cavities. The product contains a 1.23 percent fluoride ion concentration, and its acidulated nature allows for a rapid uptake of fluoride into the tooth enamel, requiring only a one-minute application to be effective. The primary purpose of this medication is to strengthen tooth enamel and increase its resistance to the acid attacks caused by plaque bacteria and sugars in the mouth. By promoting remineralization and inhibiting the demineralization of the tooth surface, it serves as an essential preventative tool for oral health. It is commonly used for both children and adults who are at a higher risk for developing tooth decay or for those who require additional protection due to certain dental conditions.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Sodium Fluoride.

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GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

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NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

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RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

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Prescribing information

From the FDA-approved label for Iris 60 Second APF. Official source: DailyMed (NLM) · Label effective Feb 2, 2022

Indications and usage
Indications and usage: A stable thixotropic fluoride treatment gel used to help prevent dental decay. For Professional Office Use Only. This product is not intended for home or unsupervised consumer use.
Dosage and administration
Dosage and administration: Shake well before use. This is a one minute of four minute fluoride gel for in-office patient use. It is normally used as a preventative caries treatment twice a year. • After thorough prophylaxis, fill two single or one dual tray, one third full with gel. Air dry teeth and insert trays into the mouth. • Instruct patient to bite down lightly but firmly for one minute (80% effectiveness) or four minutes (100% effectiveness). • Remove trays. Instruct patient to expectorate any excess gel and not to eat or drink for at least 30 minutes.
Warnings
Warnings: Keep out of reach of children. Do not swallow. If product is accidentally swallowed in quantities greater than would normally occur with a treatment gel, seek medical help or contact a Poison Control Center right away. Read directions carefully before using.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.