JAYPIRCA
Generic: pirtobrutinib
- Manufacturer
- Eli Lilly
- NDC
- 0002-6902
- RxCUI
- 2629343
- Route
- ORAL
- ICD-10 indication
- C83.10
Affordability Check
How much will you actually pay for JAYPIRCA?
In 30 seconds, see every legitimate way to afford JAYPIRCA — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About JAYPIRCA
What is this medication? Jaypirca, which contains the active ingredient pirtobrutinib, is a prescription medicine classified as a Bruton tyrosine kinase inhibitor. It is primarily used to treat adults with certain types of blood cancer, specifically mantle cell lymphoma and chronic lymphocytic leukemia or small lymphocytic lymphoma. This medication works by blocking a specific protein that helps cancer cells grow and multiply, which can help slow the progression of the disease.
This treatment is typically prescribed for patients whose cancer has returned or did not respond to previous therapies. Specifically, it is indicated for those who have already received at least two prior lines of systemic therapy, including another type of BTK inhibitor. Because Jaypirca is a non-covalent inhibitor, it can often remain effective even in patients who have developed resistance to earlier generations of similar medications.
Copay & patient assistance
Patient Copay Amount: Not Publicly Available
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: US residents ages 18 and over; qualifying patients for Lilly Cares; underinsured patients for independent foundation support
RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for pirtobrutinib.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup JAYPIRCA →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for pirtobrutinib →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How JAYPIRCA appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
62%
3,386 of 5,499 plans
Most common tier
Tier 5
On 79% of covering formularies
Prior authorization required
99%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 59 | 18% |
| Tier 2 (generic) | 2 | 1% |
| Tier 4 (non-preferred brand) | 7 | 2% |
| Tier 5 (specialty) | 259 | 79% |
| Tier 6 | 1 | 0% |
Step therapy: 0% of formularies
Quantity limits: 92% of formularies
Coverage breadth: 328 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
Related drugs
Xospata
Treats same condition · gilteritinib
Mercaptopurine
Treats same condition · Mercaptopurine
Xalkori
Treats same condition · CRIZOTINIB
Elliotts B
Treats same condition · sodium cation, sodium bicarbonate, anhydrous dextrose, magnesium sulfate, potassium chloride, calcium chloride, sodium phosphate
Mitoxantrone
Treats same condition · Mitoxantrone
ADCETRIS
Treats same condition · brentuximab vedotin
ZYNLONTA
Treats same condition · loncastuximab tesirine
Isoniazid
Treats same condition · Isoniazid
Vinblastine Sulfate
Treats same condition · VINBLASTINE SULFATE
Bendamustine
Treats same condition · BENDAMUSTINE HYDROCHLORIDE
How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.
Rare-disease navigation (specialists, trials, patient communities)
JAYPIRCA treats 3 rare conditions. For in-depth disease pages on our sister site:
UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.