Joenja
Generic: Leniolisib
- Manufacturer
- Pharming
- NDC
- 71274-170
- RxCUI
- 2633015
- Route
- ORAL
- ICD-10 indication
- D81.89
Affordability Check
How much will you actually pay for Joenja?
In 30 seconds, see every legitimate way to afford Joenja — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Joenja
What is this medication? Joenja is a prescription medicine used to treat activated phosphoinositide 3-kinase delta syndrome, which is more commonly referred to as APDS. APDS is a rare genetic condition that impairs the immune system, making it difficult for the body to fight off infections and leading to various health complications. This medication specifically targets the underlying cause of the disorder by regulating an overactive enzyme that disrupts normal immune cell function.
The drug is approved for use in adults and pediatric patients who are 12 years of age and older. By acting as a selective inhibitor, Joenja helps to balance the immune response, which can reduce the size of enlarged lymph nodes and the spleen while also decreasing the frequency of respiratory infections. It is taken orally and represents the first targeted treatment option available for patients diagnosed with this specific primary immunodeficiency.
Copay & patient assistance
- Patient Copay Amount: Not Publicly Available
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Not Publicly Available
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Leniolisib.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Joenja →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for Leniolisib →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Joenja appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
4%
226 of 5,499 plans
Most common tier
Tier 5
On 77% of covering formularies
Prior authorization required
100%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 3 | 14% |
| Tier 2 (generic) | 1 | 5% |
| Tier 5 (specialty) | 17 | 77% |
| Tier 6 | 1 | 5% |
Step therapy: 0% of formularies
Quantity limits: 82% of formularies
Coverage breadth: 22 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.