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KANUMA

Generic: Sebelipase alfa

Verified·Sep 7, 2026
Manufacturer
Alexion
NDC
25682-007
RxCUI
1726979
Route
INTRAVENOUS
ICD-10 indication
E75.6

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About KANUMA

What is this medication?

Kanuma is a prescription medication used to treat people with a rare genetic condition called Lysosomal Acid Lipase deficiency, often abbreviated as LAL-D. This condition occurs when the body does not produce enough of the LAL enzyme, which is responsible for breaking down specific fats and cholesterols within the cells. Without sufficient levels of this enzyme, fats accumulate in the liver, blood vessel walls, and other organs, which can lead to severe complications such as liver disease or cardiovascular issues.

The medication works as an enzyme replacement therapy by providing a laboratory-made form of the human LAL enzyme to help the body manage fat metabolism. Kanuma is intended for use in patients of all ages, including infants, children, and adults. It is administered by a healthcare professional through an intravenous infusion to help reduce the buildup of fats in the body and improve health outcomes for those living with the deficiency.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

KANUMA treats a rare condition. For in-depth disease pages on our sister site:

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.