Linzess
Generic: linaclotide
- Manufacturer
- AbbVie
- NDC
- 0456-1201
- RxCUI
- 1307409
- Route
- ORAL
- ICD-10 indication
- K58.1
Affordability Check
How much will you actually pay for Linzess?
In 30 seconds, see every legitimate way to afford Linzess — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Linzess
What is this medication? Linzess is a prescription drug primarily used to treat certain types of digestive issues, specifically irritable bowel syndrome with constipation and chronic idiopathic constipation. It contains the active ingredient linaclotide and works by increasing the secretion of fluid in your intestines. This process helps to soften the stool and speed up bowel movements, which can alleviate symptoms like bloating and abdominal pain while promoting more regular bathroom habits.
This medication is typically taken once a day on an empty stomach, at least thirty minutes before the first meal. It is designed for adults, though it has also been approved for use in children and adolescents aged six to seventeen years who suffer from functional constipation. By acting locally in the gut, Linzess helps reduce the discomfort associated with persistent constipation without being absorbed significantly into the bloodstream.
Copay & patient assistance
- Patient Copay Amount: As little as $30 for a 30, 60, or 90-day supply.
- Maximum Annual Benefit Limit: $2,280.00 per calendar year.
- Core Eligibility Restrictions: Valid only for patients with commercial prescription insurance; must be 6 years of age or older; not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs (including TRICARE and VA); not valid for cash-paying patients; offer good only in the USA and Puerto Rico; maximum of twelve (12) prescription fills per calendar year.
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for linaclotide.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Linzess →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for linaclotide →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
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Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Linzess appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
35%
1,902 of 5,499 plans
Most common tier
Tier 3
On 75% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 59 | 18% |
| Tier 2 (generic) | 7 | 2% |
| Tier 3 (preferred brand) | 247 | 75% |
| Tier 4 (non-preferred brand) | 15 | 5% |
Step therapy: 0% of formularies
Quantity limits: 98% of formularies
Coverage breadth: 328 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.