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Matulane

Generic: procarbazine hydrochloride

Verified·Oct 26, 2026
NDC
54482-054
RxCUI
207588
Route
ORAL
ICD-10 indication
C81.9

Affordability Check

How much will you actually pay for Matulane?

In 30 seconds, see every legitimate way to afford Matulane — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

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About Matulane

What is this medication? Matulane is the brand name for the generic drug procarbazine, which is a chemotherapy medication classified as an alkylating agent. It is primarily used as part of a multi-drug regimen to treat patients diagnosed with stage three or stage four Hodgkin disease. This medication works as an antineoplastic by inhibiting the synthesis of DNA, RNA, and proteins within the body, which effectively prevents cancer cells from dividing and spreading.

The medication is typically administered in the form of an oral capsule and is often given in specific cycles that alternate with rest periods. Because it can interact with certain foods and other drugs, patients are usually required to follow a specific diet and avoid substances high in tyramine while undergoing treatment. Matulane is a potent drug that requires close medical supervision to monitor its effectiveness and manage potential side effects during the course of the cancer therapy.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Matulane appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).

Covered by plans

61%

3,369 of 5,499 plans

Most common tier

Tier 5

On 79% of covering formularies

Prior authorization required

16%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)59
18%
Tier 2 (generic)2
1%
Tier 3 (preferred brand)1
0%
Tier 4 (non-preferred brand)7
2%
Tier 5 (specialty)258
79%
Tier 61
0%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 328 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

Matulane treats 2 rare conditions. For in-depth disease pages on our sister site:

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.