How much does Me NaPhos MB Hyo 1 cost?

Pricing for Me NaPhos MB Hyo 1 varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Me NaPhos MB Hyo 1 need prior authorization?

Me NaPhos MB Hyo 1 appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Me NaPhos MB Hyo 1?

We haven't verified an active copay card or PAP for Me NaPhos MB Hyo 1 in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Me NaPhos MB Hyo 1 used to treat?

Me NaPhos MB Hyo 1 (generic: Urinary Antiseptic Antispasmodic) is indicated for Cystitis. Click any condition name on this page for more detail.

Does Me NaPhos MB Hyo 1 have a generic version?

The generic name for Me NaPhos MB Hyo 1 is Urinary Antiseptic Antispasmodic. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Me NaPhos MB Hyo 1

Generic: Urinary Antiseptic Antispasmodic

Verified·Apr 23, 2026

Manufacturer: Method
NDC: 58657-454
RxCUI: 1050325
Route: ORAL
ICD-10 indication: N30.90

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About Me NaPhos MB Hyo 1

What is this medication?

Me NaPhos MB Hyo 1 is a combination prescription medication primarily used to relieve symptoms of lower urinary tract irritation. It is frequently prescribed to alleviate discomfort, burning sensations, and the frequent or urgent need to urinate that can occur with conditions such as cystitis or after certain medical procedures involving the bladder. The medication is designed to provide symptomatic relief by addressing both the physical spasms of the urinary tract and the chemical environment of the urine.

The drug contains four active ingredients that work together to manage urinary distress. Methenamine and methylene blue act as mild antiseptics to help inhibit the growth of bacteria in the urinary tract, while sodium phosphate monobasic is used to acidify the urine, which helps the methenamine work more effectively. Additionally, hyoscyamine sulfate serves as an antispasmodic that relaxes the smooth muscles of the bladder, helping to reduce painful cramping and the constant urge to go.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Urinary Antiseptic Antispasmodic.

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GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

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NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Urinary Antiseptic Antispasmodic →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

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Prescribing information

From the FDA-approved label for Me NaPhos MB Hyo 1. Official source: DailyMed (NLM) · Label effective Oct 21, 2025

Indications and usage

INDICATION AND USAGE ME/NaPhos/MB/Hyo 1 Tablets is indicated for the treatment of symptoms of irritative voiding. Indicated for the relief of local symptoms, such as hypermotility which accompany lower urinary tract infections and as antispasmodic. Indicated for the relief of urinary tract symptoms caused by diagnostic procedures.

Dosage and administration

DOSAGE AND ADMINISTRATION Adults One tablet orally 4 times per day followed by liberal fluid intake. Older Children Dosage must be individualized by physician. Not recommended for use in children up to 6 years of age.

Warnings

WARNINGS Do not exceed recommended dosage. If rapid pulse, dizziness, or blurring of vision occurs discontinue use immediately.

Drug interactions

Drug Interactions because of this product's effect on gastrointestinal motility and gastric emptying, it may decrease the absorption of other oral medications during concurrent use such as: urinary alkalizers; thiazide diuretics (may cause the urine to become alkaline reducing the effectiveness of methenamine by inhibiting its conversion to formaldehyde); antimuscarinics (concurrent use may intensify antimuscarinic effects of hyoscyamine because of secondary antimuscarinic activities of these medications); antacids/antidiarrheals (may reduce absorption of hyoscyamine, concurrent use with antacids may cause urine to become alkaline reducing effectiveness of methenamine by inhibiting its conversion to formaldehyde) doses of these medications should be spaced 1 hour apart from doses of hyoscyamine; antimyasthenics (concurrent use with hyoscyamine may further reduce intestinal motility); ketoconazole (patients should be advised to take this combination at least 2 hours after ketoconazole); monoamine oxidase (MAO) Inhibitors (concurrent use may intensify antimuscarinic side effects, opioid (narcotic) analgesics may result in increased risk of severe constipation); sulfonamides (these drugs may precipitate with formaldehyde in the urine, increasing the danger of crystalluria). Patients should be advised that the urine may become blue to blue green and the feces may be discolored as a result of the excretion of methylene blue.

Adverse reactions

ADVERSE REACTIONS Cardiovascula r – rapid pulse, flushing Central Nervous System – blurred vision, dizziness Respiratory – shortness of breath or troubled breathing Genitourinary – difficulty micturition, acute urinary retention Gastrointestinal – dry mouth, nausea/vomiting

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Cystitis

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.