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Pretrate

Generic: Ferrous Fumarate, Folic Acid

Verified·Apr 23, 2026
NDC
59088-178
Route
ORAL
ICD-10 indication
Z34.90

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About Pretrate

What is this medication?

Pretrate is a prescription multivitamin and mineral supplement specifically formulated for women who are pregnant, planning to become pregnant, or nursing. It functions by providing essential nutrients that support the unique physiological demands of pregnancy and fetal development. Doctors often prescribe this medication to bridge nutritional gaps in a patient's diet, ensuring that both the mother and the developing baby have the necessary building blocks for a healthy gestation period.

The primary components of this supplement often include folic acid and iron, which play vital roles in prenatal health. Folic acid is crucial for preventing neural tube defects and supporting the early development of the infant's central nervous system. The iron content helps prevent iron-deficiency anemia, a common condition during pregnancy where the body requires additional red blood cells to support increased blood volume. Regular use as directed by a healthcare professional helps maintain maternal well-being and supports a healthy environment for the growing fetus.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Pretrate. Official source: DailyMed (NLM) · Label effective Sep 30, 2024

Boxed warning
WARNING Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Administration of folic acid alone is improper therapy for pernicious anemia and other megaloblastic anemias in which vitamin B 12 is deficient. Precautions Folic acid in doses above 0.1 mg daily may obscure pernicious anemia, in that hematologic remission can occur while neurological manifestations remain progressive. There is a potential danger in administering folic acid to patients with undiagnosed anemia, since folic acid may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress. This may result in severe nervous system damage before the correct diagnosis is made. Adequate doses of vitamin B 12 may prevent, halt, or improve the neurologic changes caused by pernicious anemia. The patient’s medical conditions and consumption of other drugs, herbs, and/or supplements should be considered. For use on the order of a healthcare practitioner. Call your doctor about side effects. To report side effects, call PureTek Corporation at 1-877-921-7873 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Indications and usage
Indications Pretrate is indicated to provide vitamins and minerals to women throughout pregnancy and during the postnatal period for both lactating and non-lactating mothers, and throughout the childbearing years. Pretrate may be beneficial in improving the nutritional status of women prior to conception.
Dosage and administration
Dosage and Administration: Adults (persons over 12 years of age) One (1) Pretrate caplet daily, between meals, or as directed by a physician. Do not administer to children under the age of 12.
Contraindications
Contraindications: This product is contraindicated in patients with known hypersensitivity to any of its ingredients; also, all iron compounds are contraindicated in patients with hemosiderosis, hemochromatosis, or hemolytic anemias. Pernicious anemia is a contraindication, as folic acid may obscure its signs and symptoms.
Drug interactions
Drug Interactions: Pretrate is not recommended for and should not be given to patients receiving levodopa because the action of levodopa is antagonized by pyridoxine. There is a possibility of increased bleeding due to pyridoxine interaction with anticoagulants (e.g., Aspirin, Heparin or Clopidogrel). Adverse Reactions: Folic Acid: Allergic sensitizations have been reported following both oral and parenteral administration of folic acid. Ferrous Fumarate: Gastrointestinal disturbances (anorexia, nausea, diarrhea, constipation) occur occasionally, but are usually mild and may subside with continuation of therapy. Although the absorption of iron is best when taken between meals, giving Pretrate after meals may control occasional gastrointestinal disturbances. Pretrate is best absorbed when taken at bedtime. Adverse reactions have been reported with specific vitamins and minerals but generally at levels substantially higher than those contained herein. However, allergic and idiosyncratic reactions are possible at lower levels. Iron, even at the usual recommended levels, has been associated with gastrointestinal intolerance in some patients.
Adverse reactions
Adverse Reactions: Folic Acid: Allergic sensitizations have been reported following both oral and parenteral administration of folic acid. Ferrous Fumarate: Gastrointestinal disturbances (anorexia, nausea, diarrhea, constipation) occur occasionally, but are usually mild and may subside with continuation of therapy. Although the absorption of iron is best when taken between meals, giving Pretrate after meals may control occasional gastrointestinal disturbances. Pretrate is best absorbed when taken at bedtime. Adverse reactions have been reported with specific vitamins and minerals but generally at levels substantially higher than those contained herein. However, allergic and idiosyncratic reactions are possible at lower levels. Iron, even at the usual recommended levels, has been associated with gastrointestinal intolerance in some patients.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.