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Pyridium

Generic: Phenazopyridine

Verified·Apr 23, 2026
Manufacturer
Gemini Laboratories, LLC
NDC
60846-501
RxCUI
1094104
Route
ORAL
ICD-10 indication
R30.0

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About Pyridium

What is this medication? Pyridium is a prescription medication containing the active ingredient phenazopyridine, which is primarily used to relieve symptoms of urinary tract irritation. It is effective at reducing the pain, burning, and frequent urge to urinate that often accompany urinary tract infections, injuries, or medical procedures involving the bladder. The medication functions as a local anesthetic on the mucosa of the urinary tract to provide symptomatic relief while the body recovers. Because Pyridium is an analgesic and not an antibiotic, it does not treat the underlying cause of a urinary infection and is typically used in conjunction with other treatments. It is generally recommended for short-term use, usually no more than two days when used alongside antibiotics to manage acute discomfort. A notable characteristic of this drug is that it causes the urine to turn a dark orange or reddish color, which is a normal and harmless effect that can stain clothing and contact lenses.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Pyridium. Official source: DailyMed (NLM) · Label effective Dec 16, 2023

Indications and usage
INDICATIONS AND USAGE Pyridium is indicated for the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. The use of Phenazopyridine HCl for relief of symptoms should not delay definitive diagnosis and treatment of causative conditions. Because it provides only symptomatic relief, prompt appropriate treatment of the cause of pain must be instituted and Phenazopyridine HCl should be discontinued when symptoms are controlled. The analgesic action may reduce or eliminate the need for systemic analgesics or narcotics. It is, however, compatible with antibacterial therapy and can help to relieve pain and discomfort during the interval before antibacterial therapy controls the infection. Treatment of a urinary tract infection with Phenazopyridine HCl should not exceed two days because there is a lack of evidence that the combined administration of Phenazopyridine HCl and an antibacterial provides greater benefit than administration of the antibacterial alone after two days. (See DOSAGE AND ADMINISTRATION section.)
Dosage and administration
DOSAGE AND ADMINISTRATION 100 mg Tablets: Average adult dosage is two tablets 3 times a day after meals. 200 mg Tablets: Average adult dosage is one tablet 3 times a day after meals. When used concomitantly with an antibacterial agent for the treatment of a urinary tract infection, the administration of Phenazopyridine HCl should not exceed 2 days.
Contraindications
CONTRAINDICATIONS Phenazopyridine HCl should not be used in patients who have previously exhibited hypersensitivity to it. The use of Phenazopyridine HCl is contraindicated in patients with renal insufficiency.
Adverse reactions
ADVERSE REACTIONS Headache, rash, pruritus and occasional gastrointestinal disturbance. An anaphylactoid-like reaction has been described. Methemoglobinemia, hemolytic anemia, renal and hepatic toxicity have been reported, usually at overdosage levels (see OVERDOSAGE section).

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.