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Retisert

Generic: Fluocinolone Acetonide

Data may be stale·Apr 23, 2026
Manufacturer
Bausch and Lomb
NDC
24208-416
RxCUI
1191323
Route
INTRAVITREAL
ICD-10 indication
H30.10

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About Retisert

What is this medication? Retisert is a prescription corticosteroid medication provided as a small surgical implant that is placed inside the eye. It is specifically designed to treat a condition known as chronic non-infectious uveitis that affects the posterior segment, or the back portion, of the eye. This inflammatory condition can cause vision loss if left untreated, and the implant helps manage the swelling and irritation that occurs within the ocular tissues.

The device works by slowly releasing a drug called fluocinolone acetonide directly into the eye over an extended period of time, often lasting up to thirty months. By providing a steady, low-dose delivery of medicine, Retisert helps to control long-term inflammation without the need for frequent eye injections or systemic steroid pills that can affect the entire body. Because it is a localized treatment, it aims to reduce the symptoms of uveitis while minimizing some of the side effects associated with oral medications.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Eligible patients must have commercial insurance. Additional terms and conditions apply as specified on the Focus On Access (FOA) enrollment form.
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Retisert. Official source: DailyMed (NLM) · Label effective Jul 3, 2025

Indications and usage
INDICATIONS AND USAGE Fluocinolone Acetonide Topical Solution is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION Fluocinolone Acetonide Solution is generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. In hairy sites, the hair should be parted to allow direct contact with the lesion. Occlusive dressing may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Perioral dermatitis Itching Allergic contact dermatitis Irritation Maceration of the skin Dryness Secondary infection Folliculitis Skin atrophy Hypertrichosis Striae Acneiform eruptions Miliaria Hypopigmentation
Use in pregnancy
Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

Retisert treats a rare condition. For in-depth disease pages on our sister site:

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.