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Ruxience

Generic: rituximab-pvvr

Verified·Oct 26, 2026
Manufacturer
Pfizer
NDC
0069-0238
RxCUI
2273512
Route
INTRAVENOUS
ICD-10 indication
C83.3

Affordability Check

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About Ruxience

What is this medication? Ruxience is a prescription biological medication known as a monoclonal antibody. It is specifically designed as a biosimilar to the drug Rituxan, meaning it is highly similar and provides the same clinical effects. This medication works by targeting a specific protein called CD20, which is found on the surface of B-cells in the immune system. By attaching to these cells, Ruxience helps the immune system identify and destroy them, which is why it is primarily used to treat certain types of cancer, including non-Hodgkin lymphoma and chronic lymphocytic leukemia. In addition to its use in treating blood cancers, Ruxience is used to treat rare blood vessel disorders known as granulomatosis with polyangiitis and microscopic polyangiitis. By decreasing the number of B-cells, Ruxience helps to lower the body's immune response and control the underlying inflammation associated with these chronic conditions.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Residents of the United States only; services only available for certain Pfizer Oncology medications
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

Ruxience treats 4 rare conditions. For in-depth disease pages on our sister site:

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.