SCEMBLIX
Generic: asciminib
- NDC
- 0078-1091
- RxCUI
- 2584320
- Route
- ORAL
- ICD-10 indication
- C92.10
Affordability Check
How much will you actually pay for SCEMBLIX?
In 30 seconds, see every legitimate way to afford SCEMBLIX — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About SCEMBLIX
What is this medication?
SCEMBLIX, which contains the active ingredient asciminib, is a prescription medicine used to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia, often referred to as Ph+ CML, in the chronic phase. This medication is specifically indicated for patients who have already been treated with two or more tyrosine kinase inhibitor medications. Additionally, it is approved for the treatment of adult patients with Ph+ CML in the chronic phase who have a specific genetic alteration known as the T315I mutation.
As a targeted therapy, SCEMBLIX functions as a kinase inhibitor that works differently than many other leukemia treatments. It is known as a STAMP inhibitor, meaning it specifically targets the ABL myristoyl pocket of the BCR-ABL1 protein. By binding to this specific site, the medication blocks the signals that tell the cancerous white blood cells to grow and multiply. This unique mechanism helps to control the overproduction of these cells and is used when other standard treatments have not been effective or cannot be tolerated by the patient.
Copay & patient assistance
- Patient Copay Amount: As little as $0
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Valid only for patients with private (commercial) insurance; not valid for patients enrolled in federal or state healthcare programs including Medicare, Medicaid, TRICARE, VA, or DoD; valid only in the United States and Puerto Rico; patient must have a valid prescription and insurance coverage for the product.
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for asciminib.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup SCEMBLIX →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for asciminib →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How SCEMBLIX appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
67%
3,671 of 5,499 plans
Most common tier
Tier 5
On 79% of covering formularies
Prior authorization required
99%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 59 | 18% |
| Tier 2 (generic) | 2 | 1% |
| Tier 4 (non-preferred brand) | 7 | 2% |
| Tier 5 (specialty) | 259 | 79% |
| Tier 6 | 1 | 0% |
Step therapy: 0% of formularies
Quantity limits: 95% of formularies
Coverage breadth: 328 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.
Rare-disease navigation (specialists, trials, patient communities)
SCEMBLIX treats a rare condition. For in-depth disease pages on our sister site:
UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.