How much does SOHONOS cost?

Pricing for SOHONOS varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does SOHONOS need prior authorization?

SOHONOS appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for SOHONOS?

Yes — the manufacturer copay card link is available on this page. A patient assistance program is also available for qualifying patients. Eligibility typically depends on insurance type and income. Click the CTA buttons above to apply directly through the manufacturer's portal.

What is SOHONOS used to treat?

SOHONOS (generic: palovarotene) is indicated for Myositis ossificans. Click any condition name on this page for more detail.

Does SOHONOS have a generic version?

The generic name for SOHONOS is palovarotene. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

SOHONOS

Generic: palovarotene

Verified·Oct 26, 2026

Manufacturer: Ipsen
NDC: 15054-0010
RxCUI: 2663960
Route: ORAL
ICD-10 indication: M61.1

Affordability Check

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About SOHONOS

What is this medication?

Sohonos is a prescription medicine containing the active ingredient palovarotene. It is specifically approved to treat adults and children with a rare genetic condition called fibrodysplasia ossificans progressiva, which is often abbreviated as FOP. This disorder causes muscle and connective tissues like tendons and ligaments to be replaced by bone outside the normal skeleton, a process known as heterotopic ossification. Sohonos is indicated for use in females aged 8 years and older and males aged 10 years and older who have reached a specific level of skeletal maturity.

The medication works as a selective retinoic acid receptor gamma agonist. By targeting these specific receptors, it helps to decrease the formation of new abnormal bone that occurs after flare-ups or due to ongoing disease progression. While it does not cure the underlying condition, it is used to reduce the volume of new heterotopic ossification, which can help preserve mobility and physical function for patients living with FOP. It is typically taken as a daily capsule, with the dosage increased by a healthcare provider during times of active flare-ups.

Copay & patient assistance

Patient Copay Amount: Not Publicly Available
Maximum Annual Benefit Limit: Not Publicly Available (Text states an annual calendar year maximum benefit applies, but the specific amount is not listed)
Core Eligibility Restrictions:
Must be a United States resident or resident of its territories.
Must be enrolled in the IPSEN CARES program.
Must have commercial insurance; patients enrolled in government-funded programs (including Medicare Part B, Medicare Part D, Medicaid, Medigap, VA, DoD, or TRICARE) are ineligible.
Residents of Massachusetts or Rhode Island may only receive assistance for the cost of the Ipsen product, not for related medical services (injections).
Patients receiving assistance through another foundation, program, or free trial are ineligible during the current enrollment year.
Use of the program for reimbursement through Flexible Spending Accounts (FSA), Health Savings Accounts (HSA), or Health Reimbursement Accounts (HRA) is prohibited.
RxBIN, PCN, and Group numbers: Not Publicly Available

Copay card →Patient Assistance Program →

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for palovarotene.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup SOHONOS →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for palovarotene →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Myositis ossificans

Medicare Part D coverage

How SOHONOS appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).

Covered by plans

174 of 5,499 plans

Most common tier

Tier 5

On 76% of covering formularies

Prior authorization required

100%

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	3	18%
Tier 2 (generic)	1	6%
Tier 5 (specialty)	13	76%

Step therapy: 0% of formularies

Quantity limits: 59% of formularies

Coverage breadth: 17 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.