Spravato
Generic: Esketamine Hydrochloride
- Manufacturer
- Janssen
- NDC
- 50458-028
- RxCUI
- 2119381
- Route
- NASAL
- ICD-10 indication
- F33.41
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About Spravato
What is this medication?
Spravato is the brand name for esketamine, a prescription nasal spray used primarily for adults suffering from treatment-resistant depression. This classification applies to individuals with major depressive disorder who have not responded adequately to at least two different antidepressant treatments. Additionally, it is indicated for the rapid reduction of depressive symptoms in adults with major depressive disorder who are experiencing an acute suicidal crisis or have thoughts of self-harm.
Because of the potential for serious side effects such as sedation, dissociation, and the risk of misuse, Spravato is strictly administered under the supervision of a healthcare provider in a certified medical setting. It is not a standalone treatment but is typically used in conjunction with a daily oral antidepressant. Patients must remain at the treatment center for monitoring for at least two hours after receiving their dose to ensure their safety and well-being.
Copay & patient assistance
- Patient Copay Amount: Not Publicly Available
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Not Publicly Available
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Esketamine Hydrochloride.
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GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
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NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
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RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
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Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.