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Sterile Water

Generic: STERILE WATER

Verified·Apr 23, 2026
Manufacturer
Pfizer
NDC
71872-7290
Route
INTRAMUSCULAR
ICD-10 indication
Z51.9

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About Sterile Water

What is this medication? Sterile water for injection is a clear, colorless, and odorless liquid that is used as a solvent or diluent for other medications. It is specifically processed to ensure it is free of bacteria and other microorganisms, as well as fever-inducing substances called pyrogens. Healthcare providers use it to dissolve or dilute drugs that need to be administered through various routes such as intravenous, intramuscular, or subcutaneous injection. Because it contains no antimicrobial agents or added buffers, it is intended for single-use applications to prepare a solution for immediate delivery to a patient.

It is important to note that sterile water should never be injected directly into a patient without first mixing it with a medication to make the solution isotonic. Injecting pure sterile water can cause red blood cells to burst, a serious condition known as hemolysis. In clinical settings, it may also be used for non-injection purposes such as irrigating wounds, cleaning medical equipment, or filling humidifiers for respiratory treatments. The specific use depends on the packaging and label instructions, as different versions are designed for either injection or topical irrigation.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Sterile Water. Official source: DailyMed (NLM) · Label effective Sep 19, 2022

Indications and usage
INDICATIONS AND USAGE This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.
Dosage and administration
DOSAGE AND ADMINISTRATION The volume of the preparation to be used for diluting or dissolving any drug for injection is dependent on the vehicle concentration, dose and route of administration as recommended by the manufacturer. This parenteral should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Contraindications
CONTRAINDICATIONS Sterile Water for Injection, USP must be made approximately isotonic prior to use.
Warnings
WARNINGS Intravenous administration of Sterile Water for Injection without a solute may result in hemolysis.
Adverse reactions
ADVERSE REACTIONS Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate countermeasures, and if possible, retrieve and save the remainder of the unused vehicle for examination.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.