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Strong Iodine Solution

Generic: Lugols Solution Strong Iodine Solution

Verified·Apr 23, 2026
NDC
48433-230
ICD-10 indication
E05.9

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About Strong Iodine Solution

What is this medication? Strong Iodine Solution, which is frequently referred to as Lugols solution, is a medication that combines elemental iodine with potassium iodide. It is primarily used by healthcare providers to treat hyperthyroidism and to prepare the thyroid gland for surgical removal. When taken before a thyroidectomy, it helps decrease the vascularity and size of the gland, which makes the procedure safer and reduces the risk of excessive bleeding. It achieves this by temporarily slowing down the release of thyroid hormones into the body.

This solution is also utilized as a protective agent during radiation emergencies involving the release of radioactive iodine. By filling the thyroid gland with stable iodine, the medication prevents the organ from absorbing harmful radioactive particles. It is also sometimes used as a topical antiseptic or as a diagnostic tool in certain medical exams. Because it is highly concentrated, it must be diluted and used only under strict medical supervision to prevent complications such as iodine toxicity or stomach irritation.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Strong Iodine Solution. Official source: DailyMed (NLM) · Label effective Jan 8, 2025

Indications and usage
INDICATIONS Strong Iodine Solution, containing 5 percent of iodine and 10 percent of potassium iodide, is employed in the prophylaxis of simple and colloid goiters and in the treatment of exophthalmic goiter. It can be used alone as a preoperative preparation but is now most commonly used concomitantly with propylthiouracil and other antithyroid drugs. When used with these drugs, Strong Iodine Solution produces involution of the hyperplastic gland thus making a less triable and vascular gland for thyroidectomy. In addition, it has an additive antithyroid action that helps make the patient enthyroid faster than if the antithyroid drugs were used alone.
Dosage and administration
DOSAGE Strong Iodine Solution is for oral use only. The usual dosage of Strong Iodine Solution is 2 to 6 drops (0.1 to 0.3 ml) three times daily taken in water after meals for two or three weeks prior to operation. In thyroid crisis the dosage is 1 ml three times a day.
Contraindications
CONTRAINDICATIONS The use of iodides may be contraindicated in patients with tuberculosis because it is believed they may cause a breakdown of healing lesions. The use of iodides is contraindicated in patients with iododerma, laryngeal edema, and swelling of salivary glands or increased salivation upon previous exposure to iodides. Strong Iodine Solution is ineffective in the treatment of postoperative thyroid crisis.
Warnings
WARNINGS Prolonged therapy may cause iodism. USE IN PREGNANCY: The drug readily crosses the placental barrier and may affect the fetus if used during pregnancy.
Adverse reactions
ADVERSE REACTIONS Ingestion of large quantities of Strong Iodine Solution may cause abdominal pain, nausea, vomiting and diarrhea. Average doses may cause skin rash.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.