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TREMFYA

Generic: Guselkumab

Data may be stale·Apr 23, 2026
Manufacturer
Janssen
NDC
57894-640
RxCUI
1928686
Route
SUBCUTANEOUS
ICD-10 indication
L40.0

Affordability Check

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About TREMFYA

What is this medication? Tremfya is a prescription brand-name medication known generically as guselkumab. It is primarily used to treat adults living with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. Additionally, it is approved for the treatment of adults with active psoriatic arthritis. The medication works by targeting a specific protein in the body called interleukin-23, which is involved in the inflammatory response that causes skin cells to overproduce and joints to become swollen.

This medication is administered via an injection under the skin, typically starting with two initial doses and then continuing with maintenance doses every eight weeks. By blocking the action of interleukin-23, Tremfya helps to clear skin plaques and reduce the joint pain and stiffness associated with psoriatic arthritis. Because it affects the immune system, healthcare providers usually screen patients for infections like tuberculosis before starting treatment and monitor for potential side effects during the course of therapy.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How TREMFYA appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).

Covered by plans

70%

3,875 of 5,499 plans

Most common tier

Tier 5

On 80% of covering formularies

Prior authorization required

99%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)33
16%
Tier 2 (generic)1
0%
Tier 4 (non-preferred brand)7
3%
Tier 5 (specialty)163
80%

Step therapy: 0% of formularies

Quantity limits: 71% of formularies

Coverage breadth: 204 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

—

Medicare Part D

Yes——

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.