WELIREG
Generic: belzutifan
- Manufacturer
- Merck
- NDC
- 0006-5331
- RxCUI
- 2567231
- Route
- ORAL
- ICD-10 indication
- Q85.89
Affordability Check
How much will you actually pay for WELIREG?
In 30 seconds, see every legitimate way to afford WELIREG — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About WELIREG
What is this medication?
Welireg is a prescription medication used to treat adults with von Hippel-Lindau disease who need treatment for renal cell carcinoma, central nervous system hemangioblastomas, or pancreatic neuroendocrine tumors. It is specifically intended for patients who do not require immediate surgery for these conditions. The drug belongs to a class of medications called HIF-2 alpha inhibitors, which work by blocking a protein that helps certain tumors grow and spread under low-oxygen conditions.
Additionally, Welireg is used for the treatment of adults with advanced renal cell carcinoma, which is the most common type of kidney cancer. This application is for patients whose cancer has continued to grow after receiving previous treatments, including an immunotherapy drug known as a PD-1 or PD-L1 inhibitor and a targeted therapy called a VEGF tyrosine kinase inhibitor. By interfering with specific proteins, the medication helps slow the progression of advanced kidney tumors.
Copay & patient assistance
- Patient Copay Amount: Not Publicly Available
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Not Publicly Available
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for belzutifan.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup WELIREG →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for belzutifan →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How WELIREG appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
53%
2,893 of 5,499 plans
Most common tier
Tier 5
On 79% of covering formularies
Prior authorization required
99%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 59 | 18% |
| Tier 2 (generic) | 2 | 1% |
| Tier 4 (non-preferred brand) | 7 | 2% |
| Tier 5 (specialty) | 259 | 79% |
| Tier 6 | 1 | 0% |
Step therapy: 0% of formularies
Quantity limits: 75% of formularies
Coverage breadth: 328 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.
Rare-disease navigation (specialists, trials, patient communities)
WELIREG treats a rare condition. For in-depth disease pages on our sister site:
UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.