How much does Xenon, Xe-133 cost?

Pricing for Xenon, Xe-133 varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Xenon, Xe-133 need prior authorization?

Xenon, Xe-133 appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Xenon, Xe-133?

We haven't verified an active copay card or PAP for Xenon, Xe-133 in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Xenon, Xe-133 used to treat?

Xenon, Xe-133 (generic: Xenon) is indicated for Lung Disease. Click any condition name on this page for more detail.

Does Xenon, Xe-133 have a generic version?

The generic name for Xenon, Xe-133 is Xenon. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Xenon, Xe-133

Generic: Xenon

Verified·Apr 23, 2026

Manufacturer: Curium
NDC: 69945-097
Route: RESPIRATORY (INHALATION)
ICD-10 indication: J98.4

Affordability Check

How much will you actually pay for Xenon, Xe-133?

In 30 seconds, see every legitimate way to afford Xenon, Xe-133 — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

Check my options →

About Xenon, Xe-133

What is this medication? Xenon Xe-133 is a radioactive gas used as a diagnostic imaging agent to evaluate the condition of the lungs and blood flow. It is primarily administered through inhalation during a pulmonary ventilation study, which helps physicians observe how air is distributed throughout the respiratory system. By using a specialized gamma camera to track the gas as it moves, medical professionals can detect abnormalities such as obstructed airways or areas of poor ventilation, which is often crucial for diagnosing conditions like chronic obstructive pulmonary disease or assessing overall lung health.

In addition to its role in respiratory diagnosis, this medication is sometimes used to measure blood flow in the brain or other organs. Because Xenon Xe-133 is an inert gas, it does not react with body tissues and is eventually removed from the body through the breath once the imaging is complete. It is frequently used in combination with other scans to help identify pulmonary embolisms, allowing doctors to compare the airflow in the lungs with blood circulation to pinpoint specific areas where a potential blockage might be occurring.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Xenon.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Xenon, Xe-133 →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Xenon →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Xenon, Xe-133. Official source: DailyMed (NLM) · Label effective Oct 16, 2024

Indications and usage

INDICATIONS AND USAGE Xenon Xe 133 Gas has been shown to be valuable for diagnostic inhalation studies for the evaluation of pulmonary function, for imaging the lungs and may also be applied to assessment of cerebral blood flow.

Dosage and administration

DOSAGE AND ADMINISTRATION Xenon Xe 133 Gas is administered by inhalation from a closed respirator system or spirometer. The final patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration. The recommended activity range employed for inhalation by the average patient (70 kg) is: Pulmonary function including imaging: 74 to 1110 megabecquerels (2 to 30 millicuries) Cerebral blood flow: 370 to 1110 megabecquerels (10 to 30 millicuries) This may be administered as a bolus into the tubing near the patient's mouthpiece or mask after the completion of a tidal exhalation, or by rebreathing for a period of approximately 5 minutes of the Xenon Xe 133 gas in equilibrium with the air contained in the closed system at concentrations of the radionuclide that may vary from 37 to 222 megabecquerels (1.0 to 6.0 millicuries) per liter.

Contraindications

CONTRAINDICATIONS None known.

Warnings

WARNINGS Xenon Xe 133 Gas delivery systems, i.e., respirators or spirometers, and associated tubing assemblies must be leakproof to avoid loss of radioactivity into the laboratory environs not specifically protected by exhaust systems. Xenon Xe 133 Gas adheres to some plastics and rubber and should not be allowed to stand in tubing or respirator containers. Loss of radioactivity due to such adherence may render the study nondiagnostic.

Adverse reactions

ADVERSE REACTIONS Adverse reactions specifically attributable to Xenon Xe 133 Gas have not been reported.

Use in pregnancy

Pregnancy Animal reproduction studies have not been conducted with Xenon Xe 133 Gas. It is also not known whether Xenon Xe 133 Gas can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Xenon Xe 133 Gas should be given to a pregnant woman only if clearly needed. Ideally, all examinations that use radiopharmaceuticals, especially those elective in nature, of a woman of childbearing capability should be performed during the first few (approximately 10) days following the onset of menses.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Lung Disease

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.