How much does Xyzal cost?

Pricing for Xyzal varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Xyzal need prior authorization?

Xyzal appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Xyzal?

We haven't verified an active copay card or PAP for Xyzal in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Xyzal used to treat?

Xyzal (generic: Levocetirizine dihydrochloride) is indicated for Hay Fever, Itching, Allergic Rhinitis. Click any condition name on this page for more detail.

Does Xyzal have a generic version?

The generic name for Xyzal is Levocetirizine dihydrochloride. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Xyzal

Generic: Levocetirizine dihydrochloride

Verified·Apr 23, 2026

Manufacturer: UCB
NDC: 41167-3510
RxCUI: 855172
Route: ORAL
ICD-10 indication: J30.89

Affordability Check

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About Xyzal

What is this medication?

Xyzal, known generically as levocetirizine dihydrochloride, is an antihistamine medication primarily used to relieve symptoms associated with seasonal and year-round allergies. It is commonly prescribed to treat allergic rhinitis, providing relief from symptoms such as sneezing, a runny nose, and itchy or watery eyes. By blocking the action of histamine, a substance in the body that causes allergic reactions, the medication helps patients manage their discomfort during high-pollen seasons or when exposed to indoor allergens like dust and pet dander.

Beyond respiratory issues, Xyzal is also indicated for the treatment of chronic idiopathic urticaria, which involves long-term, unexplained hives and skin itching. It helps to reduce the severity of skin rashes and the frequency of hive outbreaks in both adults and children. The medication is available in tablet and oral solution forms, allowing for flexible dosing based on the patient's age and specific medical needs as determined by a healthcare professional.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Levocetirizine dihydrochloride.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Xyzal →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Levocetirizine dihydrochloride →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Xyzal. Official source: DailyMed (NLM) · Label effective Mar 11, 2026

Indications and usage

Uses temporarily relieves these symptoms due to hay fever or other respiratory allergies: runny nose sneezing itchy, watery eyes itching of the nose or throat

Dosage and administration

Directions adults 65 years of age and older ■ ask a doctor adults and children 12-64 years of age ■ take 1 tablet (5 mg) once daily in the evening ■ do not take more than 1 tablet (5 mg) in 24 hours ■ ½ tablet (2.5 mg) once daily in the evening may be appropriate for less severe symptoms children 6-11 years of age ■ take ½ tablet (2.5 mg) once daily in the evening ■ do not take more than ½ tablet (2.5 mg) in 24 hours children under 6 years of age ■ do not use consumers with kidney disease ■ do not use

Warnings

Warnings Do not use if you have kidney disease if you have ever had an allergic reaction to this product or any of its ingredients or to an antihistamine containing cetirizine Ask a doctor before use if you have ever had trouble urinating or emptying your bladder When using this product drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery Stop use and ask a doctor if you have trouble urinating or emptying your bladder an allergic reaction to this product occurs. Seek medical help right away. If pregnant or breast-feeding: if breast-feeding: not recommended if pregnant: ask a health professional before use Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Xyzal appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

71%

3,894 of 5,509 plans

Most common tier

Tier 1

On 50% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	166	50%
Tier 2 (generic)	154	47%
Tier 3 (preferred brand)	7	2%
Tier 4 (non-preferred brand)	2	1%

Step therapy: 0% of formularies

Quantity limits: 40% of formularies

Coverage breadth: 329 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.