How much does Zap APF cost?

Pricing for Zap APF varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Zap APF need prior authorization?

Zap APF appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Zap APF?

We haven't verified an active copay card or PAP for Zap APF in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Zap APF used to treat?

Zap APF (generic: Sodium Fluoride) is indicated for Fluoride Treatment. Click any condition name on this page for more detail.

Does Zap APF have a generic version?

The generic name for Zap APF is Sodium Fluoride. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Zap APF

Generic: Sodium Fluoride

Verified·Apr 23, 2026

Manufacturer: Crosstex
NDC: 24794-100
RxCUI: 245593
Route: DENTAL
ICD-10 indication: Z29.3

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About Zap APF

What is this medication? Zap APF is a prescription-strength topical fluoride treatment used in dentistry to prevent dental caries, also known as cavities. It consists of acidulated phosphate fluoride, which provides a high concentration of fluoride ions to the tooth enamel. This process helps to strengthen the outer layer of the teeth and makes them more resistant to the acidic byproducts of oral bacteria that lead to decay.

This medication is most commonly applied by a dental professional during a professional cleaning or checkup. It is specifically recommended for individuals who have a moderate to high risk of tooth decay, such as those with orthodontic appliances, dry mouth, or a history of frequent cavities. By enhancing the remineralization of the tooth structure, Zap APF serves as a proactive measure to maintain long-term oral health and integrity.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Sodium Fluoride.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Zap APF →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Sodium Fluoride →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Zap APF. Official source: DailyMed (NLM) · Label effective Jan 20, 2022

Indications and usage

Indications & Usage: This is a prescription fluoride treatment gel used to help prevent dental decay. For Professional Use Only. This product is not intended for home or unsupervised consumer use.

Dosage and administration

Dosage and Administration: Shake well before use. This is a one minute or four minute fluoride gel for in-office patient use. It is normally used as a preventative caries treatment two times a year. 1. After thorough prophylaxsis, fill two single or one dual tray one third full with gel. Air dry teeth and insert trays into the mouth. 2. Instruct patient to bite down lightly but firmly for one minute (80% effectiveness) or four minutes (100% effectiveness). 3. Remove trays. Instruct patient to expectorate any excess gel and not to eat or drink for at least 30 minutes.

Warnings

Warnings: Keep out of reach of children. Do not swallow. If product is accidentally swallowed in quantities greater than would normally occur with a treatment gel, seek medical help or contact a Poison Control Center right away. Read directions carefully before using.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Fluoride Treatment

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.