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ZO Skin Health Pigment Control Creme Hydroquinone

Generic: Hydroquinone

Data may be stale·Apr 23, 2026
Manufacturer
ZO Skin Health
NDC
42851-037
RxCUI
1235391
Route
TOPICAL
ICD-10 indication
L81.1

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About ZO Skin Health Pigment Control Creme Hydroquinone

What is this medication? ZO Skin Health Pigment Control Creme is a prescription-strength topical treatment designed to address various forms of hyperpigmentation. It contains 4 percent hydroquinone, which is a highly effective skin-bleaching agent used to lighten dark patches on the skin. This medication is primarily prescribed to treat conditions such as melasma, chloasma, solar lentigines, and freckles that may result from sun exposure, hormonal changes, or skin injuries.

The cream works by inhibiting the production of melanin, the pigment responsible for skin color, in the overactive melanocytes of the skin. By suppressing the enzymatic conversion of tyrosine to melanin, the treatment gradually fades existing dark spots and prevents new ones from forming. Because hydroquinone is a potent medical ingredient, it is typically used for a limited duration under the supervision of a healthcare professional to ensure safety and avoid potential side effects.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for ZO Skin Health Pigment Control Creme Hydroquinone. Official source: DailyMed (NLM) · Label effective Oct 23, 2025

Indications and usage
Uses helps prevent sunburn If used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun
Dosage and administration
Directions apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m.–2 p.m. wear long-sleeved shirts, pants, hats, and sunglasses children under 6 months: Ask a doctor
Warnings
Warnings For external use only Do not use on damaged or broken skin Stop use and ask a doctor if rash occurs When using this product keep out of eyes. Rinse with water to remove. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.