Skip to main content

ZO Skin Health Pigment Control Creme Hydroquinone

Generic: Hydroquinone

Verified·Apr 23, 2026
Manufacturer
ZO Skin Health
NDC
42851-037
RxCUI
1235391
Route
TOPICAL
ICD-10 indication
L81.1

Affordability Check

How much will you actually pay for ZO Skin Health Pigment Control Creme Hydroquinone?

In 30 seconds, see every legitimate way to afford ZO Skin Health Pigment Control Creme Hydroquinone — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

Check my options →

About ZO Skin Health Pigment Control Creme Hydroquinone

What is this medication? ZO Skin Health Pigment Control Creme is a prescription-strength topical treatment designed to address various forms of hyperpigmentation. It contains 4 percent hydroquinone, which is a highly effective skin-bleaching agent used to lighten dark patches on the skin. This medication is primarily prescribed to treat conditions such as melasma, chloasma, solar lentigines, and freckles that may result from sun exposure, hormonal changes, or skin injuries.

The cream works by inhibiting the production of melanin, the pigment responsible for skin color, in the overactive melanocytes of the skin. By suppressing the enzymatic conversion of tyrosine to melanin, the treatment gradually fades existing dark spots and prevents new ones from forming. Because hydroquinone is a potent medical ingredient, it is typically used for a limited duration under the supervision of a healthcare professional to ensure safety and avoid potential side effects.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for ZO Skin Health Pigment Control Creme Hydroquinone. Official source: DailyMed (NLM) · Label effective Apr 22, 2022

Dosage and administration
DOSAGE AND ADMINISTRATION Apply 2 pumps (1g) to affected areas twice a day or as directed by a physician. Always use sunscreen protection. (See enclosed package insert for full prescribing information.)
Warnings
WARNINGS Keep out of reach of children. Contains Sodium Metabisulfite, a sulfite that may cause serious allergic-type reactions, including anaphylactic symptoms (e.g., hives, itching) and life-threatening or less-severe asthmatic episodes in certain susceptible persons. For external use only. Avoid contact with the eyes. Some users may experience a mild skin irritation. If skin irritation becomes severe, stop use and consult a physician. Do not use on children under 12 years of age unless directed by a physician. If swallowed, get medical help or contact a poison control center right away.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.