Horizon --- **Verification of current ownership:** Actimmune (interferon gamma-1b) is a biologic drug used to treat chronic granulomatous disease and malignant osteopetrosis. The rights to the drug were acquired by **Horizon Therapeutics** (formerly Horizon Pharma) in 2014. While **Amgen** acquired Horizon Therapeutics in October 2023, Horizon remains the primary manufacturer and legal holder of the Biologics License Application (BLA) in official FDA records (such as the Purple Book). Following the instruction to strip legal suffixes and descriptors like "Therapeutics" (which is analogous to "Pharmaceuticals"), the core company name is **Horizon**.

Drugs from Horizon --- **Verification of current ownership:** Actimmune (interferon gamma-1b) is a biologic drug used to treat chronic granulomatous disease and malignant osteopetrosis. The rights to the drug were acquired by **Horizon Therapeutics** (formerly Horizon Pharma) in 2014. While **Amgen** acquired Horizon Therapeutics in October 2023, Horizon remains the primary manufacturer and legal holder of the Biologics License Application (BLA) in official FDA records (such as the Purple Book). Following the instruction to strip legal suffixes and descriptors like "Therapeutics" (which is analogous to "Pharmaceuticals"), the core company name is **Horizon**. (1)

• ACTIMMUNE

  Interferon gamma-1b

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