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Affordability Check

How to afford Prempro, Premphase

Pick how you're covered. We'll show you the cheapest legitimate way to get Prempro, Premphase — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.

How are you covered for prescriptions?

Pick the one that fits you. We'll show you the cheapest way to get this drug.

Pick an option above to see your specific path.

Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.

About Prempro, Premphase and its cost

What is this medication? Prempro and Premphase are prescription medications used for hormone replacement therapy in postmenopausal women who still have their uterus. These medications contain a combination of two female hormones, conjugated estrogens and medroxyprogesterone acetate. They are primarily prescribed to treat moderate to severe symptoms of menopause, such as hot flashes and night sweats, as well as to address vaginal dryness, burning, and irritation caused by decreasing estrogen levels.

In addition to managing menopausal symptoms, these medications are also used to help prevent postmenopausal osteoporosis, a condition that causes bones to become thin and weak. Because they contain a progestin, they are specifically designed for women who have not had a hysterectomy to help lower the risk of developing cancer of the lining of the uterus. Patients typically take these tablets once daily, following a continuous or sequential schedule as determined by their healthcare provider.

Prempro, Premphase is made by Pfizer. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.

Common questions

What's the cheapest way to afford Prempro, Premphase?

It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.

Can I use a copay card with Medicare for Prempro, Premphase?

No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Pfizer has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.

Does my Medicare Part D plan cover Prempro, Premphase?

Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.

How long does a Patient Assistance Program take?

Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.

What if I have a high-deductible plan?

For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.

Are there charity grants for Menopause?

Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.

More about Prempro, Premphase