Affordability Check
How to afford TUKYSA
Generic name: tucatinib
Pick how you're covered. We'll show you the cheapest legitimate way to get TUKYSA — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.
Pick an option above to see your specific path.
Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.
About TUKYSA and its cost
What is this medication? TUKYSA is a prescription medicine used to treat adults with HER2-positive breast cancer that is advanced or has spread to other parts of the body, including the brain. It is typically prescribed for patients whose cancer cannot be removed by surgery and who have already received one or more other anti-HER2-based treatments. This medication is taken in combination with two other drugs, trastuzumab and capecitabine, to help manage the disease.
This drug is also used to treat adults with a specific type of HER2-positive colorectal cancer that has spread or is unresectable. It is intended for patients with RAS wild-type tumors that have progressed after treatment with certain types of chemotherapy. When used for colorectal cancer, TUKYSA is administered in combination with trastuzumab to block the signals that encourage cancer cells to grow and divide.
TUKYSA is made by a pharmaceutical manufacturer. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.
Common questions
What's the cheapest way to afford TUKYSA?
It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.
Can I use a copay card with Medicare for TUKYSA?
No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But the manufacturer has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.
Does my Medicare Part D plan cover TUKYSA?
Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.
How long does a Patient Assistance Program take?
Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.
What if I have a high-deductible plan?
For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.
Are there charity grants for Colorectal Cancer?
Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.
More about TUKYSA
Full TUKYSA drug page
FDA label, prior authorization rules, full indications list
More options for Colorectal Cancer
Drugs, grants, and assistance for this condition
Guide to Patient Assistance Programs
How PAPs work, who qualifies, typical wait times
If your insurance denied coverage
5-level appeal playbook — Medicare has a 60% win rate at Level 3