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Affordability Check

How to afford XIAFLEX

Generic name: collagenase clostridium histolyticum

Pick how you're covered. We'll show you the cheapest legitimate way to get XIAFLEX — your insurance copay, manufacturer savings, charity grants, or cash price. It takes 30 seconds and we never ask for your personal information.

How are you covered for prescriptions?

Pick the one that fits you. We'll show you the cheapest way to get this drug.

Pick an option above to see your specific path.

Different insurance means different laws and different savings. For example, Medicare patients cannot use manufacturer copay cards (federal law) — but the manufacturer almost always has a Patient Assistance Program that gives the drug free.

About XIAFLEX and its cost

What is this medication? Xiaflex is a prescription medicine containing the enzyme collagenase clostridium histolyticum, which is designed to break down collagen buildup in specific areas of the body. It is used to treat adult patients with Dupuytren contracture, a condition where a thickening of tissue in the palm causes one or more fingers to stay in a bent position. By injecting the medication directly into the thickened cord, healthcare providers can weaken the tissue, allowing them to manually straighten the finger and improve the patient's range of motion.

The medication is also indicated for the treatment of adult men with Peyronie disease who have a palpable plaque and a curvature of the penis of at least thirty degrees at the start of therapy. In this application, Xiaflex is injected into the scar tissue or plaque that causes the curvature. This process helps to reduce the physical deformity and the symptoms associated with the condition. Because of the complexity of these procedures, Xiaflex is only administered by trained medical professionals in a doctor's office or clinic.

XIAFLEX is made by Endo. Like most brand-name drugs, it's priced at a high list price — but patients rarely pay that list price. The options above are the real paths most people use to get it affordably.

Common questions

What's the cheapest way to afford XIAFLEX?

It depends on your insurance. On Medicare, apply for the manufacturer's Patient Assistance Program (PAP) — it gives the drug free if you meet income requirements. With private insurance, the manufacturer copay card usually drops your copay to $0-$25. Uninsured patients should compare the PAP with Cost Plus Drugs cash price.

Can I use a copay card with Medicare for XIAFLEX?

No — federal law (the Anti-Kickback Statute) prohibits manufacturer copay cards on Medicare, Medicaid, TriCare, and VA prescriptions. But Endo has a separate Patient Assistance Program for Medicare beneficiaries. Check the options above.

Does my Medicare Part D plan cover XIAFLEX?

Part D coverage varies by plan. We query the CMS Prescription Drug Plan file to show you what percentage of plans cover it and at what tier. For your exact copay, pick "Medicare" above and check your plan's Summary of Benefits, or log in to Medicare.gov.

How long does a Patient Assistance Program take?

Most PAPs take 2-6 weeks from application to first fill. Ask the manufacturer about a "bridge supply" — many will ship 30 days free while your application is being reviewed so you don't go without the drug.

What if I have a high-deductible plan?

For generics, Cost Plus Drugs cash price is often cheaper than your deductible-phase copay. For brand names, the manufacturer copay card almost always wins. A GoodRx coupon can be a last resort for uncovered drugs, but it doesn't count toward your deductible.

Are there charity grants for Dupuytren's contracture?

Charities like HealthWell Foundation, PAN Foundation, Good Days, and the National Organization for Rare Disorders provide copay help for specific conditions. Funds often run out mid-year — apply early. We list the specific grants for your condition in the options above.

More about XIAFLEX