XIAFLEX

What is this medication? Xiaflex is a prescription medicine containing the enzyme collagenase clostridium histolyticum, which is designed to break down collagen buildup in specific areas of the body. It is used to treat adult patients with Dupuytren contracture, a condition where a thickening of tissue in the palm causes one or more fingers to stay in a bent position. By injecting the medication directly into the thickened cord, healthcare providers can weaken the tissue, allowing them to manually straighten the finger and improve the patient's range of motion.

The medication is also indicated for the treatment of adult men with Peyronie disease who have a palpable plaque and a curvature of the penis of at least thirty degrees at the start of therapy. In this application, Xiaflex is injected into the scar tissue or plaque that causes the curvature. This process helps to reduce the physical deformity and the symptoms associated with the condition. Because of the complexity of these procedures, Xiaflex is only administered by trained medical professionals in a doctor's office or clinic.